Glucocorticoid treatment of MCMV infected newborn mice attenuates CNS inflammation and limits deficits in cerebellar development.

Infection of the developing fetus with human cytomegalovirus (HCMV) is a major cause of central nervous system disease in infants and children; however, mechanism(s) of disease associated with this intrauterine infection remain poorly understood. Utilizing a mouse model of HCMV infection of the deve...

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Autores principales: Kate Kosmac, Glenn R Bantug, Ester P Pugel, Djurdjica Cekinovic, Stipan Jonjic, William J Britt
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/1c7cd2f8965641fd8bb1acdc18fc03b1
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