Glucocorticoid treatment of MCMV infected newborn mice attenuates CNS inflammation and limits deficits in cerebellar development.

Infection of the developing fetus with human cytomegalovirus (HCMV) is a major cause of central nervous system disease in infants and children; however, mechanism(s) of disease associated with this intrauterine infection remain poorly understood. Utilizing a mouse model of HCMV infection of the deve...

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Auteurs principaux: Kate Kosmac, Glenn R Bantug, Ester P Pugel, Djurdjica Cekinovic, Stipan Jonjic, William J Britt
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/1c7cd2f8965641fd8bb1acdc18fc03b1
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