Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients

Background and Aim: The aim of the study was to evaluate the effect of nonsurgical periodontal therapy on clinical, renal, and hematological parameters at baseline and 3 months postoperatively on chronic kidney disease (CKD) patients undergoing hemodialysis. This comparative interventional study was...

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Autores principales:	Sheethel Menon Vrinda, Arun Sadasivan, Elizabeth Koshi, Beena Unnikrishnan, Nikhil Das Chandradas, Indhuja Raveendran Saraswathi
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	dialysis inflammation periodontitis renal insufficiency treatment Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/1c80ce4da56e4342b8e4cf8792a21bfd
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spelling	oai:doaj.org-article:1c80ce4da56e4342b8e4cf8792a21bfd2021-11-12T10:23:42ZEffect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients0972-124X10.4103/jisp.jisp_32_20https://doaj.org/article/1c80ce4da56e4342b8e4cf8792a21bfd2021-01-01T00:00:00Zhttp://www.jisponline.com/article.asp?issn=0972-124X;year=2021;volume=25;issue=6;spage=485;epage=490;aulast=Vrindahttps://doaj.org/toc/0972-124XBackground and Aim: The aim of the study was to evaluate the effect of nonsurgical periodontal therapy on clinical, renal, and hematological parameters at baseline and 3 months postoperatively on chronic kidney disease (CKD) patients undergoing hemodialysis. This comparative interventional study was conducted among CKD patients undergoing hemodialysis. Materials and Methods: This study included chronic periodontitis (CP) patients divided into three groups Group I: CKD patients undergoing hemodialysis for less than a year; Group II: CKD patients undergoing hemodialysis for more than a year; and Group III: systemically healthy CP patients. Clinical parameters (bleeding on probing [BOP], probing pocket depth (PPD), and clinical attachment level [CAL]) were recorded at baseline (T0), 1 month (T1), and 3 months after scaling and root planing (SRP) (T2). C-reactive protein (CRP) and transferrin saturation (TSAT) were observed at T0 and at T2. Paired t-test and Chi-square test were applied to find the statistical significance (P < 0.05 was considered statistically significant at 95% confidence interval) between the T0 and T2 time within the groups. Results: Clinical parameters such as PPD and CAL decreased with statistical significance in Group III alone, whereas BOP decreased with statistical significance in all the three groups. The study showed statistically significant reduction of CRP (in Group I and Group III) and TSAT increased with statistical significance in all the three groups after SRP. Conclusion: This suggests that SRP can bring an improvement in the systemic markers in CP patients under hemodialysis. However, we need a longitudinal study with a larger sample size to confirm the results.Sheethel Menon VrindaArun SadasivanElizabeth KoshiBeena UnnikrishnanNikhil Das ChandradasIndhuja Raveendran SaraswathiWolters Kluwer Medknow Publicationsarticledialysisinflammationperiodontitisrenal insufficiencytreatmentDentistryRK1-715ENJournal of Indian Society of Periodontology, Vol 25, Iss 6, Pp 485-490 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	dialysis inflammation periodontitis renal insufficiency treatment Dentistry RK1-715
spellingShingle	dialysis inflammation periodontitis renal insufficiency treatment Dentistry RK1-715 Sheethel Menon Vrinda Arun Sadasivan Elizabeth Koshi Beena Unnikrishnan Nikhil Das Chandradas Indhuja Raveendran Saraswathi Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
description	Background and Aim: The aim of the study was to evaluate the effect of nonsurgical periodontal therapy on clinical, renal, and hematological parameters at baseline and 3 months postoperatively on chronic kidney disease (CKD) patients undergoing hemodialysis. This comparative interventional study was conducted among CKD patients undergoing hemodialysis. Materials and Methods: This study included chronic periodontitis (CP) patients divided into three groups Group I: CKD patients undergoing hemodialysis for less than a year; Group II: CKD patients undergoing hemodialysis for more than a year; and Group III: systemically healthy CP patients. Clinical parameters (bleeding on probing [BOP], probing pocket depth (PPD), and clinical attachment level [CAL]) were recorded at baseline (T0), 1 month (T1), and 3 months after scaling and root planing (SRP) (T2). C-reactive protein (CRP) and transferrin saturation (TSAT) were observed at T0 and at T2. Paired t-test and Chi-square test were applied to find the statistical significance (P < 0.05 was considered statistically significant at 95% confidence interval) between the T0 and T2 time within the groups. Results: Clinical parameters such as PPD and CAL decreased with statistical significance in Group III alone, whereas BOP decreased with statistical significance in all the three groups. The study showed statistically significant reduction of CRP (in Group I and Group III) and TSAT increased with statistical significance in all the three groups after SRP. Conclusion: This suggests that SRP can bring an improvement in the systemic markers in CP patients under hemodialysis. However, we need a longitudinal study with a larger sample size to confirm the results.
format	article
author	Sheethel Menon Vrinda Arun Sadasivan Elizabeth Koshi Beena Unnikrishnan Nikhil Das Chandradas Indhuja Raveendran Saraswathi
author_facet	Sheethel Menon Vrinda Arun Sadasivan Elizabeth Koshi Beena Unnikrishnan Nikhil Das Chandradas Indhuja Raveendran Saraswathi
author_sort	Sheethel Menon Vrinda
title	Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
title_short	Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
title_full	Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
title_fullStr	Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
title_full_unstemmed	Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
title_sort	effect of nonsurgical periodontal therapy on c-reactive protein and iron indices in hemodialysis patients
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/1c80ce4da56e4342b8e4cf8792a21bfd
work_keys_str_mv	AT sheethelmenonvrinda effectofnonsurgicalperiodontaltherapyoncreactiveproteinandironindicesinhemodialysispatients AT arunsadasivan effectofnonsurgicalperiodontaltherapyoncreactiveproteinandironindicesinhemodialysispatients AT elizabethkoshi effectofnonsurgicalperiodontaltherapyoncreactiveproteinandironindicesinhemodialysispatients AT beenaunnikrishnan effectofnonsurgicalperiodontaltherapyoncreactiveproteinandironindicesinhemodialysispatients AT nikhildaschandradas effectofnonsurgicalperiodontaltherapyoncreactiveproteinandironindicesinhemodialysispatients AT indhujaraveendransaraswathi effectofnonsurgicalperiodontaltherapyoncreactiveproteinandironindicesinhemodialysispatients
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Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients

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