3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

Abstract The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3...

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Autores principales:	Alexander Juerchott, Muhammad Abdullah Saleem, Tim Hilgenfeld, Christian Freudlsperger, Sebastian Zingler, Christopher J. Lux, Martin Bendszus, Sabine Heiland
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1c8515e9b265420eb65be831a7b2003e
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spelling	oai:doaj.org-article:1c8515e9b265420eb65be831a7b2003e2021-12-02T15:08:49Z3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility10.1038/s41598-018-31384-82045-2322https://doaj.org/article/1c8515e9b265420eb65be831a7b2003e2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-31384-8https://doaj.org/toc/2045-2322Abstract The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 different positions. In vivo MRI scans were performed on 3 volunteers in five head positions. For each in vivo scan, 27 landmarks were determined from which 19 angles and 26 distances were calculated. Statistical analysis was performed using Bland-Altman analysis, the two one-sided tests procedure and repeated measures one-way analysis of variance. In comparison to ground truth, all MRI-based phantom measurements showed statistical equivalence (p < 0.001) and an excellent agreement in Bland-Altman analysis (bias ranges: −0.090–0.044°, −0.220–0.241 mm). In vivo cephalometric analysis was highly reproducible among the five different head positions in all study participants, without statistical differences for all angles and distances (p > 0.05). Ranges between maximum and minimum in vivo values were consistently smaller than 2° and 2 mm, respectively (average ranges: 0.88°/0.87 mm). In conclusion, this study demonstrates that accurate and reproducible 3D cephalometric analysis can be performed without exposure to ionizing radiation using MRI.Alexander JuerchottMuhammad Abdullah SaleemTim HilgenfeldChristian FreudlspergerSebastian ZinglerChristopher J. LuxMartin BendszusSabine HeilandNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Alexander Juerchott Muhammad Abdullah Saleem Tim Hilgenfeld Christian Freudlsperger Sebastian Zingler Christopher J. Lux Martin Bendszus Sabine Heiland 3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility
description	Abstract The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 different positions. In vivo MRI scans were performed on 3 volunteers in five head positions. For each in vivo scan, 27 landmarks were determined from which 19 angles and 26 distances were calculated. Statistical analysis was performed using Bland-Altman analysis, the two one-sided tests procedure and repeated measures one-way analysis of variance. In comparison to ground truth, all MRI-based phantom measurements showed statistical equivalence (p < 0.001) and an excellent agreement in Bland-Altman analysis (bias ranges: −0.090–0.044°, −0.220–0.241 mm). In vivo cephalometric analysis was highly reproducible among the five different head positions in all study participants, without statistical differences for all angles and distances (p > 0.05). Ranges between maximum and minimum in vivo values were consistently smaller than 2° and 2 mm, respectively (average ranges: 0.88°/0.87 mm). In conclusion, this study demonstrates that accurate and reproducible 3D cephalometric analysis can be performed without exposure to ionizing radiation using MRI.
format	article
author	Alexander Juerchott Muhammad Abdullah Saleem Tim Hilgenfeld Christian Freudlsperger Sebastian Zingler Christopher J. Lux Martin Bendszus Sabine Heiland
author_facet	Alexander Juerchott Muhammad Abdullah Saleem Tim Hilgenfeld Christian Freudlsperger Sebastian Zingler Christopher J. Lux Martin Bendszus Sabine Heiland
author_sort	Alexander Juerchott
title	3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility
title_short	3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility
title_full	3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility
title_fullStr	3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility
title_full_unstemmed	3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility
title_sort	3d cephalometric analysis using magnetic resonance imaging: validation of accuracy and reproducibility
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1c8515e9b265420eb65be831a7b2003e
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3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

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