ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis
Intracellular vesicle transport can be regulated by Brefeldin‐A ADP‐Ribosylated Substrate (BARS) during vesicle fission. Here, the authors show that NADH generated by aldehyde dehydrogenase 7A1 (ALDH7A1) inhibits intracellular transport by targeting BARS and inhibiting COPI vesicle fission during si...
Guardado en:
Autores principales: | Jia-Shu Yang, Jia-Wei Hsu, Seung-Yeol Park, Stella Y. Lee, Jian Li, Ming Bai, Claudia Alves, William Tseng, Xavier Michelet, I-Cheng Ho, Victor W. Hsu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1c893257dab047c3a63455ff031c0ff7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Potassium starvation in yeast: mechanisms of homeostasis revealed by mathematical modeling.
por: Matthias Kahm, et al.
Publicado: (2012) -
Transcriptome analysis and prognosis of ALDH isoforms in human cancer
por: Peter Mu-Hsin Chang, et al.
Publicado: (2018) -
The cellular mechanisms of body iron homeostasis
por: NUÑEZ,MARCO T, et al.
Publicado: (2000) -
Intracellular ATP Concentration and Implication for Cellular Evolution
por: Jack V. Greiner, et al.
Publicado: (2021) -
Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?
por: Anastasia Minenkova, et al.
Publicado: (2021)