Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype

Abstract Most tumors undergo metabolic reprogramming towards glycolysis, the so-called Warburg effect, to support growth and survival. Overexpression of IF1, the physiological inhibitor of the F0F1ATPase, has been related to this phenomenon and appears to be a relevant marker in cancer. Environmenta...

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Auteurs principaux: Kévin Hardonnière, Morgane Fernier, Isabelle Gallais, Baharia Mograbi, Normand Podechard, Eric Le Ferrec, Nathalie Grova, Brice Appenzeller, Agnès Burel, Martine Chevanne, Odile Sergent, Laurence Huc, Sylvie Bortoli, Dominique Lagadic-Gossmann
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/1ca6f3d18d574609b106ab4e3f97c2b7
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