AT1 receptor induced alterations in histone H2A reveal novel insights into GPCR control of chromatin remodeling.

Chronic activation of angiotensin II (AngII) type 1 receptor (AT(1)R), a prototypical G protein-coupled receptor (GPCR) induces gene regulatory stress which is responsible for phenotypic modulation of target cells. The AT(1)R-selective drugs reverse the gene regulatory stress in various cardiovascul...

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Autores principales: Rajaganapathi Jagannathan, Suma Kaveti, Russell W Desnoyer, Belinda Willard, Michael Kinter, Sadashiva S Karnik
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/1cb7ddca70b748c7819f1c9bbc8186a3
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