Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery

Wellingson S Paiva1, Erich T Fonoff1, Marco A Marcolin2, Hector N Cabrera1, Manoel J Teixeira11Division of Functional Neurosurgery, Hospital das Clinicas, 2TMS Laboratory of the Psychiatry Institute, Hospital das Clinicas, University of S&atilde;o Paulo School of Medicine, S&atilde;o...

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Autores principales:	Paiva WS, Teixeira MJ, Marcolin MA, Cabrera HN, Fonoff ET
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/1cbbd19a6c43478cbcb2b05b98f550a3
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spelling	oai:doaj.org-article:1cbbd19a6c43478cbcb2b05b98f550a32021-12-02T02:26:51ZCortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery1176-63281178-2021https://doaj.org/article/1cbbd19a6c43478cbcb2b05b98f550a32012-05-01T00:00:00Zhttp://www.dovepress.com/cortical-mapping-with-navigated-transcranial-magnetic-stimulation-in-l-a9820https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Wellingson S Paiva1, Erich T Fonoff1, Marco A Marcolin2, Hector N Cabrera1, Manoel J Teixeira11Division of Functional Neurosurgery, Hospital das Clinicas, 2TMS Laboratory of the Psychiatry Institute, Hospital das Clinicas, University of S&atilde;o Paulo School of Medicine, S&atilde;o Paulo, BrazilAbstract: Transcranial magnetic stimulation (TMS) is a promising method for both investigation and therapeutic treatment of psychiatric and neurologic disorders and, more recently, for brain mapping. This study describes the application of navigated TMS for motor cortex mapping in patients with a brain tumor located close to the precentral gyrus.Materials and methods: In this prospective study, six patients with low-grade gliomas in or near the precentral gyrus underwent TMS, and their motor responses were correlated to locations in the cortex around the lesion, generating a functional map overlaid on three-dimensional magnetic resonance imaging (MRI) scans of the brain. To determine the accuracy of this new method, we compared TMS mapping with the gold standard mapping with direct cortical electrical stimulation in surgery. The same navigation system and TMS-generated map were used during the surgical resection procedure.Results: The motor cortex could be clearly mapped using both methods. The locations corresponding to the hand and forearm, found during intraoperative mapping, showed a close spatial relationship to the homotopic areas identified by TMS mapping. The mean distance between TMS and direct cortical electrical stimulation (DES) was 4.16 &plusmn; 1.02 mm (range: 2.56&ndash;5.27 mm).Conclusion: Preoperative mapping of the motor cortex with navigated TMS prior to brain tumor resection is a useful presurgical planning tool with good accuracy.Keywords: transcranial magnetic stimulation, cortical mapping, brain tumor, motor cortexPaiva WSTeixeira MJMarcolin MACabrera HNFonoff ETDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2012, Iss default, Pp 197-201 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Paiva WS Teixeira MJ Marcolin MA Cabrera HN Fonoff ET Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
description	Wellingson S Paiva1, Erich T Fonoff1, Marco A Marcolin2, Hector N Cabrera1, Manoel J Teixeira11Division of Functional Neurosurgery, Hospital das Clinicas, 2TMS Laboratory of the Psychiatry Institute, Hospital das Clinicas, University of S&atilde;o Paulo School of Medicine, S&atilde;o Paulo, BrazilAbstract: Transcranial magnetic stimulation (TMS) is a promising method for both investigation and therapeutic treatment of psychiatric and neurologic disorders and, more recently, for brain mapping. This study describes the application of navigated TMS for motor cortex mapping in patients with a brain tumor located close to the precentral gyrus.Materials and methods: In this prospective study, six patients with low-grade gliomas in or near the precentral gyrus underwent TMS, and their motor responses were correlated to locations in the cortex around the lesion, generating a functional map overlaid on three-dimensional magnetic resonance imaging (MRI) scans of the brain. To determine the accuracy of this new method, we compared TMS mapping with the gold standard mapping with direct cortical electrical stimulation in surgery. The same navigation system and TMS-generated map were used during the surgical resection procedure.Results: The motor cortex could be clearly mapped using both methods. The locations corresponding to the hand and forearm, found during intraoperative mapping, showed a close spatial relationship to the homotopic areas identified by TMS mapping. The mean distance between TMS and direct cortical electrical stimulation (DES) was 4.16 &plusmn; 1.02 mm (range: 2.56&ndash;5.27 mm).Conclusion: Preoperative mapping of the motor cortex with navigated TMS prior to brain tumor resection is a useful presurgical planning tool with good accuracy.Keywords: transcranial magnetic stimulation, cortical mapping, brain tumor, motor cortex
format	article
author	Paiva WS Teixeira MJ Marcolin MA Cabrera HN Fonoff ET
author_facet	Paiva WS Teixeira MJ Marcolin MA Cabrera HN Fonoff ET
author_sort	Paiva WS
title	Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
title_short	Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
title_full	Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
title_fullStr	Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
title_full_unstemmed	Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
title_sort	cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/1cbbd19a6c43478cbcb2b05b98f550a3
work_keys_str_mv	AT paivaws corticalmappingwithnavigatedtranscranialmagneticstimulationinlowgradegliomasurgery AT teixeiramj corticalmappingwithnavigatedtranscranialmagneticstimulationinlowgradegliomasurgery AT marcolinma corticalmappingwithnavigatedtranscranialmagneticstimulationinlowgradegliomasurgery AT cabrerahn corticalmappingwithnavigatedtranscranialmagneticstimulationinlowgradegliomasurgery AT fonoffet corticalmappingwithnavigatedtranscranialmagneticstimulationinlowgradegliomasurgery
_version_	1718402453305556992

Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery

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