Design and study of in vivo bone formation characteristics of biodegradable bioceramic

In this paper, two groups of titanium alloy and biodegradable ceramic scaffolds with the same pore structure were designed, and the cell proliferation and bone tissue growth of the two groups were studied by cell proliferation experiment and animal experiment. The results show that the biological pr...

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Autores principales:	Su Wang, Zhili Huang, Linlin Liu, Zhang'ao Shi, Juncai Liu, Zhong Li, Yongqiang Hao
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Scaffold Bone ingrowth Titanium alloy Silicate 3D printing Animal experiment Materials of engineering and construction. Mechanics of materials TA401-492
Acceso en línea:	https://doaj.org/article/1cbe93bcaf154fa4bee7d0ebdae8d617
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spelling	oai:doaj.org-article:1cbe93bcaf154fa4bee7d0ebdae8d6172021-11-12T04:24:55ZDesign and study of in vivo bone formation characteristics of biodegradable bioceramic0264-127510.1016/j.matdes.2021.110242https://doaj.org/article/1cbe93bcaf154fa4bee7d0ebdae8d6172021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0264127521007978https://doaj.org/toc/0264-1275In this paper, two groups of titanium alloy and biodegradable ceramic scaffolds with the same pore structure were designed, and the cell proliferation and bone tissue growth of the two groups were studied by cell proliferation experiment and animal experiment. The results show that the biological properties of biodegradable ceramic scaffolds are obviously better than those of titanium alloy scaffolds. The cell proliferation experiment in vitro showed that with the passage of time, the number of cell proliferation and the activity of ALP in biodegradable ceramic scaffolds were higher than those in titanium alloy scaffolds. The results of animal implantation experiments show that the amount of bone tissue in the ceramic scaffold is several times than that of titanium alloy in the same implantation time, indicating that the ceramic scaffold has great research and application potential in the field of bone tissue engineering.Su WangZhili HuangLinlin LiuZhang'ao ShiJuncai LiuZhong LiYongqiang HaoElsevierarticleScaffoldBone ingrowthTitanium alloySilicate3D printingAnimal experimentMaterials of engineering and construction. Mechanics of materialsTA401-492ENMaterials & Design, Vol 212, Iss , Pp 110242- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Scaffold Bone ingrowth Titanium alloy Silicate 3D printing Animal experiment Materials of engineering and construction. Mechanics of materials TA401-492
spellingShingle	Scaffold Bone ingrowth Titanium alloy Silicate 3D printing Animal experiment Materials of engineering and construction. Mechanics of materials TA401-492 Su Wang Zhili Huang Linlin Liu Zhang'ao Shi Juncai Liu Zhong Li Yongqiang Hao Design and study of in vivo bone formation characteristics of biodegradable bioceramic
description	In this paper, two groups of titanium alloy and biodegradable ceramic scaffolds with the same pore structure were designed, and the cell proliferation and bone tissue growth of the two groups were studied by cell proliferation experiment and animal experiment. The results show that the biological properties of biodegradable ceramic scaffolds are obviously better than those of titanium alloy scaffolds. The cell proliferation experiment in vitro showed that with the passage of time, the number of cell proliferation and the activity of ALP in biodegradable ceramic scaffolds were higher than those in titanium alloy scaffolds. The results of animal implantation experiments show that the amount of bone tissue in the ceramic scaffold is several times than that of titanium alloy in the same implantation time, indicating that the ceramic scaffold has great research and application potential in the field of bone tissue engineering.
format	article
author	Su Wang Zhili Huang Linlin Liu Zhang'ao Shi Juncai Liu Zhong Li Yongqiang Hao
author_facet	Su Wang Zhili Huang Linlin Liu Zhang'ao Shi Juncai Liu Zhong Li Yongqiang Hao
author_sort	Su Wang
title	Design and study of in vivo bone formation characteristics of biodegradable bioceramic
title_short	Design and study of in vivo bone formation characteristics of biodegradable bioceramic
title_full	Design and study of in vivo bone formation characteristics of biodegradable bioceramic
title_fullStr	Design and study of in vivo bone formation characteristics of biodegradable bioceramic
title_full_unstemmed	Design and study of in vivo bone formation characteristics of biodegradable bioceramic
title_sort	design and study of in vivo bone formation characteristics of biodegradable bioceramic
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/1cbe93bcaf154fa4bee7d0ebdae8d617
work_keys_str_mv	AT suwang designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic AT zhilihuang designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic AT linlinliu designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic AT zhangaoshi designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic AT juncailiu designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic AT zhongli designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic AT yongqianghao designandstudyofinvivoboneformationcharacteristicsofbiodegradablebioceramic
_version_	1718431276164186112

Design and study of in vivo bone formation characteristics of biodegradable bioceramic

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