Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing

Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing

The functional significance of start site choice in promoter architectures is little understood. Here the authors identify in zebrafish development and mammalian cells a class of dual-initiation promoters, in which non-canonical YC dinucleotides reflecting 5’-TOP/TCT initiation are intertwined with...

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Autores principales: Chirag Nepal, Yavor Hadzhiev, Piotr Balwierz, Estefanía Tarifeño-Saldivia, Ryan Cardenas, Joseph W. Wragg, Ana-Maria Suzuki, Piero Carninci, Bernard Peers, Boris Lenhard, Jesper B. Andersen, Ferenc Müller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/1ccdccedb09b4f3faf2cec376a66c412
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