MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma

Imaging tracking of the migration of cell-based drug delivery systems are needed for expanding their clinical application for glioma. Here they report inflammation activatable engineered neutrophils containing doxorubicin-loaded magnetic mesoporous silica nanoparticles to image and actively target b...

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Autores principales: Meiying Wu, Haixian Zhang, Changjun Tie, Chunhong Yan, Zhiting Deng, Qian Wan, Xin Liu, Fei Yan, Hairong Zheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1cda3a0cc012453584a4e599c34b2518
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Sumario:Imaging tracking of the migration of cell-based drug delivery systems are needed for expanding their clinical application for glioma. Here they report inflammation activatable engineered neutrophils containing doxorubicin-loaded magnetic mesoporous silica nanoparticles to image and actively target brain tumors after resection.