MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma

Imaging tracking of the migration of cell-based drug delivery systems are needed for expanding their clinical application for glioma. Here they report inflammation activatable engineered neutrophils containing doxorubicin-loaded magnetic mesoporous silica nanoparticles to image and actively target b...

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Autores principales: Meiying Wu, Haixian Zhang, Changjun Tie, Chunhong Yan, Zhiting Deng, Qian Wan, Xin Liu, Fei Yan, Hairong Zheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1cda3a0cc012453584a4e599c34b2518
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spelling oai:doaj.org-article:1cda3a0cc012453584a4e599c34b25182021-12-02T15:34:22ZMR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma10.1038/s41467-018-07250-62041-1723https://doaj.org/article/1cda3a0cc012453584a4e599c34b25182018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07250-6https://doaj.org/toc/2041-1723Imaging tracking of the migration of cell-based drug delivery systems are needed for expanding their clinical application for glioma. Here they report inflammation activatable engineered neutrophils containing doxorubicin-loaded magnetic mesoporous silica nanoparticles to image and actively target brain tumors after resection.Meiying WuHaixian ZhangChangjun TieChunhong YanZhiting DengQian WanXin LiuFei YanHairong ZhengNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Meiying Wu
Haixian Zhang
Changjun Tie
Chunhong Yan
Zhiting Deng
Qian Wan
Xin Liu
Fei Yan
Hairong Zheng
MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
description Imaging tracking of the migration of cell-based drug delivery systems are needed for expanding their clinical application for glioma. Here they report inflammation activatable engineered neutrophils containing doxorubicin-loaded magnetic mesoporous silica nanoparticles to image and actively target brain tumors after resection.
format article
author Meiying Wu
Haixian Zhang
Changjun Tie
Chunhong Yan
Zhiting Deng
Qian Wan
Xin Liu
Fei Yan
Hairong Zheng
author_facet Meiying Wu
Haixian Zhang
Changjun Tie
Chunhong Yan
Zhiting Deng
Qian Wan
Xin Liu
Fei Yan
Hairong Zheng
author_sort Meiying Wu
title MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
title_short MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
title_full MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
title_fullStr MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
title_full_unstemmed MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
title_sort mr imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/1cda3a0cc012453584a4e599c34b2518
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