Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy
Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized experimental models may be helpful. Here, we modeled tacr...
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Auteurs principaux: | , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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The Korean Association of Internal Medicine
2021
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Accès en ligne: | https://doaj.org/article/1cdcf2c8f8544d2a884a0e270371f0bb |
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