Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy

Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized experimental models may be helpful. Here, we modeled tacr...

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Auteurs principaux: Jin Won Kim, Sun Ah Nam, Eunjeong Seo, Jong Young Lee, Dohui Kim, Ji Hyeon Ju, Sun Woo Lim, Hong Lim Kim, Hyung Wook Kim, Chul Woo Yang, Jin Kim, Dong Sung Kim, Yong Kyun Kim
Format: article
Langue:EN
Publié: The Korean Association of Internal Medicine 2021
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Accès en ligne:https://doaj.org/article/1cdcf2c8f8544d2a884a0e270371f0bb
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