Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment

Introduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant m...

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Autores principales: Liliana CEPOI, Ludmila RUDI, Tatiana CHIRIAC, Vera MISCU, Valeriu RUDIC
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Publicado: Asociatia de Biosiguranta si Biosecuritate 2020
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Acceso en línea:https://doaj.org/article/1ce3648b4d15460dbbca0e92c7c78b1c
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spelling oai:doaj.org-article:1ce3648b4d15460dbbca0e92c7c78b1c2021-12-02T13:34:41ZMalondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment2887-34582587-3466https://doaj.org/article/1ce3648b4d15460dbbca0e92c7c78b1c2020-03-01T00:00:00Zhttps://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/35/21https://doaj.org/toc/2887-3458https://doaj.org/toc/2587-3466Introduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant methods and markers of nanoparticle toxicity is a current research direction. Material and methods. The strain of red microalgae Porphyridium cruentum CNM-AR-01, known as a lipid manufacturer, was used as object of study. The toxic effect of CdSe (3-7 nm), ZnSe (40 nm), and ZnS (30-35 nm) nanoparticles was tested. The amount of malondialdehyde was determined based on thiobarbituric acid reactive substances. Results. A close correlation between the amount of biomass and malondialdehyde in the cells of red microalgae Porphyridium cruentum has been established for nanoparticle concentration ranges which have a toxic effect on Porphyridium cruentum. Conclusions. Malondialdehyde can be considered as a marker of nanoparticle toxicity.Liliana CEPOILudmila RUDITatiana CHIRIACVera MISCUValeriu RUDICAsociatia de Biosiguranta si Biosecuritatearticlenanoparticlestoxicity testsmalondialdehydeporphyridium cruentumMedicineRScienceQENFRRORUOne Health & Risk Management, Vol 1, Iss 1, Pp 64-71 (2020)
institution DOAJ
collection DOAJ
language EN
FR
RO
RU
topic nanoparticles
toxicity tests
malondialdehyde
porphyridium cruentum
Medicine
R
Science
Q
spellingShingle nanoparticles
toxicity tests
malondialdehyde
porphyridium cruentum
Medicine
R
Science
Q
Liliana CEPOI
Ludmila RUDI
Tatiana CHIRIAC
Vera MISCU
Valeriu RUDIC
Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
description Introduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant methods and markers of nanoparticle toxicity is a current research direction. Material and methods. The strain of red microalgae Porphyridium cruentum CNM-AR-01, known as a lipid manufacturer, was used as object of study. The toxic effect of CdSe (3-7 nm), ZnSe (40 nm), and ZnS (30-35 nm) nanoparticles was tested. The amount of malondialdehyde was determined based on thiobarbituric acid reactive substances. Results. A close correlation between the amount of biomass and malondialdehyde in the cells of red microalgae Porphyridium cruentum has been established for nanoparticle concentration ranges which have a toxic effect on Porphyridium cruentum. Conclusions. Malondialdehyde can be considered as a marker of nanoparticle toxicity.
format article
author Liliana CEPOI
Ludmila RUDI
Tatiana CHIRIAC
Vera MISCU
Valeriu RUDIC
author_facet Liliana CEPOI
Ludmila RUDI
Tatiana CHIRIAC
Vera MISCU
Valeriu RUDIC
author_sort Liliana CEPOI
title Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
title_short Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
title_full Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
title_fullStr Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
title_full_unstemmed Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
title_sort malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
publisher Asociatia de Biosiguranta si Biosecuritate
publishDate 2020
url https://doaj.org/article/1ce3648b4d15460dbbca0e92c7c78b1c
work_keys_str_mv AT lilianacepoi malondialdehydeapotentialmarkerofnanoparticletoxicityinanaquaticenvironment
AT ludmilarudi malondialdehydeapotentialmarkerofnanoparticletoxicityinanaquaticenvironment
AT tatianachiriac malondialdehydeapotentialmarkerofnanoparticletoxicityinanaquaticenvironment
AT veramiscu malondialdehydeapotentialmarkerofnanoparticletoxicityinanaquaticenvironment
AT valeriurudic malondialdehydeapotentialmarkerofnanoparticletoxicityinanaquaticenvironment
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