Gene expression drives the evolution of dominance

Dominance is difficult to measure in natural populations as it is confounded with fitness. Here, Huber et al. developed a new approach to co-estimate dominance and selection coefficients, and found that the observed relationship is best fit by a new model of dominance based on gene expression level.

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Detalles Bibliográficos
Autores principales:	Christian D. Huber, Arun Durvasula, Angela M. Hancock, Kirk E. Lohmueller
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1ce8d86d86bd4d508b553eccf0199787
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id	oai:doaj.org-article:1ce8d86d86bd4d508b553eccf0199787
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spelling	oai:doaj.org-article:1ce8d86d86bd4d508b553eccf01997872021-12-02T14:39:24ZGene expression drives the evolution of dominance10.1038/s41467-018-05281-72041-1723https://doaj.org/article/1ce8d86d86bd4d508b553eccf01997872018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05281-7https://doaj.org/toc/2041-1723Dominance is difficult to measure in natural populations as it is confounded with fitness. Here, Huber et al. developed a new approach to co-estimate dominance and selection coefficients, and found that the observed relationship is best fit by a new model of dominance based on gene expression level.Christian D. HuberArun DurvasulaAngela M. HancockKirk E. LohmuellerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christian D. Huber Arun Durvasula Angela M. Hancock Kirk E. Lohmueller Gene expression drives the evolution of dominance
description	Dominance is difficult to measure in natural populations as it is confounded with fitness. Here, Huber et al. developed a new approach to co-estimate dominance and selection coefficients, and found that the observed relationship is best fit by a new model of dominance based on gene expression level.
format	article
author	Christian D. Huber Arun Durvasula Angela M. Hancock Kirk E. Lohmueller
author_facet	Christian D. Huber Arun Durvasula Angela M. Hancock Kirk E. Lohmueller
author_sort	Christian D. Huber
title	Gene expression drives the evolution of dominance
title_short	Gene expression drives the evolution of dominance
title_full	Gene expression drives the evolution of dominance
title_fullStr	Gene expression drives the evolution of dominance
title_full_unstemmed	Gene expression drives the evolution of dominance
title_sort	gene expression drives the evolution of dominance
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1ce8d86d86bd4d508b553eccf0199787
work_keys_str_mv	AT christiandhuber geneexpressiondrivestheevolutionofdominance AT arundurvasula geneexpressiondrivestheevolutionofdominance AT angelamhancock geneexpressiondrivestheevolutionofdominance AT kirkelohmueller geneexpressiondrivestheevolutionofdominance
_version_	1718390642087821312

Gene expression drives the evolution of dominance

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