Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials

Addition of bioactive materials such as Titanium oxide (TiO2), and incorporation of bio inert ceramic such as alumina (Al2O3), into polyetheretherketone (PEEK) has been adopted as an effective approach to improve bone-implant interfaces. In this paper, hot pressing technique has been adopted as a p...

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Autores principales:	Jenan S. Kashan, Wisam K. Hamdan, Baha Fakhri
Formato:	article
Lenguaje:	EN
Publicado:	Al-Khwarizmi College of Engineering – University of Baghdad 2018
Materias:	Histology analysis, Hot pressing, Mechanical Properties, Polyetheretherketone (PEEK), TiO2/Al2O3/PEEK biocomposites. Chemical engineering TP155-156 Engineering (General). Civil engineering (General) TA1-2040
Acceso en línea:	https://doaj.org/article/1cedf79b156144e29512cdebeeca44c1
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spelling	oai:doaj.org-article:1cedf79b156144e29512cdebeeca44c12021-12-02T10:50:05ZBone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials10.22153/kej.2018.03.0041818-11712312-0789https://doaj.org/article/1cedf79b156144e29512cdebeeca44c12018-09-01T00:00:00Zhttp://alkej.uobaghdad.edu.iq/index.php/alkej/article/view/99https://doaj.org/toc/1818-1171https://doaj.org/toc/2312-0789 Addition of bioactive materials such as Titanium oxide (TiO2), and incorporation of bio inert ceramic such as alumina (Al2O3), into polyetheretherketone (PEEK) has been adopted as an effective approach to improve bone-implant interfaces. In this paper, hot pressing technique has been adopted as a production method. This technique gave a homogenous distribution of the additive materials in the proposed composite biomaterial. Different compositions and compounding temperatures have been applied to all samples. Mechanical properties and animal model have been studied in all different production conditions. The results of these new TiO2/Al2O3/PEEK biocomposites with different compositions were promising, mechanical properties within the range of human cortical bone, suitable for load bearing applications. At the same time, in vivo test shows no inflammation reaction with implanted samples. Sustained viability in contact with the sample over seven-day period, showed evidence of excellent biocompatibility in injured rejoins. Jenan S. KashanWisam K. HamdanBaha FakhriAl-Khwarizmi College of Engineering – University of BaghdadarticleHistology analysis, Hot pressing, Mechanical Properties, Polyetheretherketone (PEEK), TiO2/Al2O3/PEEK biocomposites.Chemical engineeringTP155-156Engineering (General). Civil engineering (General)TA1-2040ENAl-Khawarizmi Engineering Journal, Vol 14, Iss 3 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Histology analysis, Hot pressing, Mechanical Properties, Polyetheretherketone (PEEK), TiO2/Al2O3/PEEK biocomposites. Chemical engineering TP155-156 Engineering (General). Civil engineering (General) TA1-2040
spellingShingle	Histology analysis, Hot pressing, Mechanical Properties, Polyetheretherketone (PEEK), TiO2/Al2O3/PEEK biocomposites. Chemical engineering TP155-156 Engineering (General). Civil engineering (General) TA1-2040 Jenan S. Kashan Wisam K. Hamdan Baha Fakhri Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials
description	Addition of bioactive materials such as Titanium oxide (TiO2), and incorporation of bio inert ceramic such as alumina (Al2O3), into polyetheretherketone (PEEK) has been adopted as an effective approach to improve bone-implant interfaces. In this paper, hot pressing technique has been adopted as a production method. This technique gave a homogenous distribution of the additive materials in the proposed composite biomaterial. Different compositions and compounding temperatures have been applied to all samples. Mechanical properties and animal model have been studied in all different production conditions. The results of these new TiO2/Al2O3/PEEK biocomposites with different compositions were promising, mechanical properties within the range of human cortical bone, suitable for load bearing applications. At the same time, in vivo test shows no inflammation reaction with implanted samples. Sustained viability in contact with the sample over seven-day period, showed evidence of excellent biocompatibility in injured rejoins.
format	article
author	Jenan S. Kashan Wisam K. Hamdan Baha Fakhri
author_facet	Jenan S. Kashan Wisam K. Hamdan Baha Fakhri
author_sort	Jenan S. Kashan
title	Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials
title_short	Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials
title_full	Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials
title_fullStr	Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials
title_full_unstemmed	Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials
title_sort	bone defect animal model for hybrid polymer matrix nano composite as bone substitute biomaterials
publisher	Al-Khwarizmi College of Engineering – University of Baghdad
publishDate	2018
url	https://doaj.org/article/1cedf79b156144e29512cdebeeca44c1
work_keys_str_mv	AT jenanskashan bonedefectanimalmodelforhybridpolymermatrixnanocompositeasbonesubstitutebiomaterials AT wisamkhamdan bonedefectanimalmodelforhybridpolymermatrixnanocompositeasbonesubstitutebiomaterials AT bahafakhri bonedefectanimalmodelforhybridpolymermatrixnanocompositeasbonesubstitutebiomaterials
_version_	1718396574782980096

Bone Defect Animal Model for Hybrid Polymer Matrix Nano Composite as Bone Substitute Biomaterials

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