Chemotherapy with cisplatin: insights into intracellular pH and metabolic landscape of cancer cells in vitro and in vivo
Abstract Although cisplatin plays a central role in cancer chemotherapy, the mechanisms of cell response to this drug have been unexplored. The present study demonstrates the relationships between the intracellular pH (pHi), cell bioenergetics and the response of cervical cancer to cisplatin. pHi wa...
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Autores principales: | Marina V. Shirmanova, Irina N. Druzhkova, Maria M. Lukina, Varvara V. Dudenkova, Nadezhda I. Ignatova, Ludmila B. Snopova, Vladislav I. Shcheslavskiy, Vsevolod V. Belousov, Elena V. Zagaynova |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1d01ca27978b4309907f9f361f19b0c0 |
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