Dynamic oxygen-enhanced MRI of cerebrospinal fluid.

Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF) space. Oxy...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Taha M Mehemed, Yasutaka Fushimi, Tomohisa Okada, Akira Yamamoto, Mitsunori Kanagaki, Aki Kido, Koji Fujimoto, Naotaka Sakashita, Kaori Togashi
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1d0c4dd93e1b4d27850a5f4c2b6ad57a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1d0c4dd93e1b4d27850a5f4c2b6ad57a
record_format	dspace
spelling	oai:doaj.org-article:1d0c4dd93e1b4d27850a5f4c2b6ad57a2021-11-18T08:14:39ZDynamic oxygen-enhanced MRI of cerebrospinal fluid.1932-620310.1371/journal.pone.0100723https://doaj.org/article/1d0c4dd93e1b4d27850a5f4c2b6ad57a2014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24956198/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF) space. Oxygen enhancement of CSF has been mainly studied using MRI sequences with relatively longer time resolution such as FLAIR, and T1 value calculation. In this study, fifteen healthy volunteers were scanned using fast advanced spin echo MRI sequence with and without inversion recovery pulse in order to dynamically track oxygen enhancement of CSF. We also focused on the differences of oxygen enhancement at sulcal and ventricular CSF. Our results revealed that CSF signal after administration of oxygen shows rapid signal increase in both sulcal CSF and ventricular CSF on both sequences, with statistically significant predominant increase in sulcal CSF compared with ventricular CSF. CSF is traditionally thought to mainly form from the choroid plexus in the ventricles and is absorbed at the arachnoid villi, however, it is also believed that cerebral arterioles contribute to the production and absorption of CSF, and controversy remains in terms of the precise mechanism. Our results demonstrated rapid oxygen enhancement in sulcal CSF, which may suggest inhaled oxygen may diffuse into sulcal CSF space rapidly probably due to the abundance of pial arterioles on the brain sulci.Taha M MehemedYasutaka FushimiTomohisa OkadaAkira YamamotoMitsunori KanagakiAki KidoKoji FujimotoNaotaka SakashitaKaori TogashiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 6, p e100723 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Taha M Mehemed Yasutaka Fushimi Tomohisa Okada Akira Yamamoto Mitsunori Kanagaki Aki Kido Koji Fujimoto Naotaka Sakashita Kaori Togashi Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
description	Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF) space. Oxygen enhancement of CSF has been mainly studied using MRI sequences with relatively longer time resolution such as FLAIR, and T1 value calculation. In this study, fifteen healthy volunteers were scanned using fast advanced spin echo MRI sequence with and without inversion recovery pulse in order to dynamically track oxygen enhancement of CSF. We also focused on the differences of oxygen enhancement at sulcal and ventricular CSF. Our results revealed that CSF signal after administration of oxygen shows rapid signal increase in both sulcal CSF and ventricular CSF on both sequences, with statistically significant predominant increase in sulcal CSF compared with ventricular CSF. CSF is traditionally thought to mainly form from the choroid plexus in the ventricles and is absorbed at the arachnoid villi, however, it is also believed that cerebral arterioles contribute to the production and absorption of CSF, and controversy remains in terms of the precise mechanism. Our results demonstrated rapid oxygen enhancement in sulcal CSF, which may suggest inhaled oxygen may diffuse into sulcal CSF space rapidly probably due to the abundance of pial arterioles on the brain sulci.
format	article
author	Taha M Mehemed Yasutaka Fushimi Tomohisa Okada Akira Yamamoto Mitsunori Kanagaki Aki Kido Koji Fujimoto Naotaka Sakashita Kaori Togashi
author_facet	Taha M Mehemed Yasutaka Fushimi Tomohisa Okada Akira Yamamoto Mitsunori Kanagaki Aki Kido Koji Fujimoto Naotaka Sakashita Kaori Togashi
author_sort	Taha M Mehemed
title	Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
title_short	Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
title_full	Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
title_fullStr	Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
title_full_unstemmed	Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
title_sort	dynamic oxygen-enhanced mri of cerebrospinal fluid.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/1d0c4dd93e1b4d27850a5f4c2b6ad57a
work_keys_str_mv	AT tahammehemed dynamicoxygenenhancedmriofcerebrospinalfluid AT yasutakafushimi dynamicoxygenenhancedmriofcerebrospinalfluid AT tomohisaokada dynamicoxygenenhancedmriofcerebrospinalfluid AT akirayamamoto dynamicoxygenenhancedmriofcerebrospinalfluid AT mitsunorikanagaki dynamicoxygenenhancedmriofcerebrospinalfluid AT akikido dynamicoxygenenhancedmriofcerebrospinalfluid AT kojifujimoto dynamicoxygenenhancedmriofcerebrospinalfluid AT naotakasakashita dynamicoxygenenhancedmriofcerebrospinalfluid AT kaoritogashi dynamicoxygenenhancedmriofcerebrospinalfluid
_version_	1718421970218909696

Dynamic oxygen-enhanced MRI of cerebrospinal fluid.

Ejemplares similares