Targeted two-photon chemical apoptotic ablation of defined cell types in vivo

Investigating cell death in living organisms is hampered by a lack of techniques to induce apoptosis with spatial and temporal precision without collateral damage. Here the authors develop two-photon chemical apoptotic targeted ablation (2Phatal), allowing studies of apoptosis and its functional con...

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Autores principales: Robert A. Hill, Eyiyemisi C. Damisah, Fuyi Chen, Alex C. Kwan, Jaime Grutzendler
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1d11ab96b908497fa624c67b497b8069
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spelling oai:doaj.org-article:1d11ab96b908497fa624c67b497b80692021-12-02T15:38:50ZTargeted two-photon chemical apoptotic ablation of defined cell types in vivo10.1038/ncomms158372041-1723https://doaj.org/article/1d11ab96b908497fa624c67b497b80692017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15837https://doaj.org/toc/2041-1723Investigating cell death in living organisms is hampered by a lack of techniques to induce apoptosis with spatial and temporal precision without collateral damage. Here the authors develop two-photon chemical apoptotic targeted ablation (2Phatal), allowing studies of apoptosis and its functional consequencesin vivo.Robert A. HillEyiyemisi C. DamisahFuyi ChenAlex C. KwanJaime GrutzendlerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Robert A. Hill
Eyiyemisi C. Damisah
Fuyi Chen
Alex C. Kwan
Jaime Grutzendler
Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
description Investigating cell death in living organisms is hampered by a lack of techniques to induce apoptosis with spatial and temporal precision without collateral damage. Here the authors develop two-photon chemical apoptotic targeted ablation (2Phatal), allowing studies of apoptosis and its functional consequencesin vivo.
format article
author Robert A. Hill
Eyiyemisi C. Damisah
Fuyi Chen
Alex C. Kwan
Jaime Grutzendler
author_facet Robert A. Hill
Eyiyemisi C. Damisah
Fuyi Chen
Alex C. Kwan
Jaime Grutzendler
author_sort Robert A. Hill
title Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
title_short Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
title_full Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
title_fullStr Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
title_full_unstemmed Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
title_sort targeted two-photon chemical apoptotic ablation of defined cell types in vivo
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/1d11ab96b908497fa624c67b497b8069
work_keys_str_mv AT robertahill targetedtwophotonchemicalapoptoticablationofdefinedcelltypesinvivo
AT eyiyemisicdamisah targetedtwophotonchemicalapoptoticablationofdefinedcelltypesinvivo
AT fuyichen targetedtwophotonchemicalapoptoticablationofdefinedcelltypesinvivo
AT alexckwan targetedtwophotonchemicalapoptoticablationofdefinedcelltypesinvivo
AT jaimegrutzendler targetedtwophotonchemicalapoptoticablationofdefinedcelltypesinvivo
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