The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans
lncRNAs are transcriptional regulators, but little is known of them functioning as negative feedback regulators of inflammation in humans. Here, the authors show that the human lncRNA LUCAT1 sequesters STAT1 to limit JAK/STAT signaling and the inflammatory response to viral infection or TLR stimulat...
Guardado en:
Autores principales: | Shiuli Agarwal, Tim Vierbuchen, Sreya Ghosh, Jennie Chan, Zhaozhao Jiang, Richard K. Kandasamy, Emiliano Ricci, Katherine A. Fitzgerald |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1d15ab27155343e5bc98b57512bbe82b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
An autoregulatory negative feedback loop controls thermomorphogenesis in Arabidopsis.
por: Sanghwa Lee, et al.
Publicado: (2021) -
MMAB promotes negative feedback control of cholesterol homeostasis
por: Leigh Goedeke, et al.
Publicado: (2021) -
Negative feedback enables fast and flexible collective decision-making in ants.
por: Christoph Grüter, et al.
Publicado: (2012) -
Alternating Positive and Negative Feedback Control Model Based on Catastrophe Theories
por: Wenkai Huang, et al.
Publicado: (2021) -
Brain activity elicited by positive and negative feedback in preschool-aged children.
por: Xiaoqin Mai, et al.
Publicado: (2011)