The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia

In Drosophila, ensheathing glia encase the neuropil but their function is not well understood. Here the authors show a surprising role of ensheathing glia in regulating glutamate homeostasis and locomotion which is controlled by the sulfite oxidase Shopper.

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Detalles Bibliográficos
Autores principales: Nils Otto, Zvonimir Marelja, Andreas Schoofs, Holger Kranenburg, Jonas Bittern, Kerem Yildirim, Dimitri Berh, Maria Bethke, Silke Thomas, Sandra Rode, Benjamin Risse, Xiaoyi Jiang, Michael Pankratz, Silke Leimkühler, Christian Klämbt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1d164f61f1ee44d3bf7f3ff6c54fc0ab
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Sumario:In Drosophila, ensheathing glia encase the neuropil but their function is not well understood. Here the authors show a surprising role of ensheathing glia in regulating glutamate homeostasis and locomotion which is controlled by the sulfite oxidase Shopper.