A tRNA half modulates translation as stress response in Trypanosoma brucei

A tRNA half modulates translation as stress response in Trypanosoma brucei

Trypanosoma brucei mainly relies on translational regulation to adjust gene expression, but details are unclear. Here the authors show that, under stress conditions, tRNAThr half level increases, associates with ribosomes and polysomes, and stimulates protein synthesis by facilitating mRNA loading.

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Detalles Bibliográficos
Autores principales: Roger Fricker, Rebecca Brogli, Hannes Luidalepp, Leander Wyss, Michel Fasnacht, Oliver Joss, Marek Zywicki, Mark Helm, André Schneider, Marina Cristodero, Norbert Polacek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/1d23c87897e1460f9d583fc47617f772
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