Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity

Aim. To identify risk factors of macro-microvascular lesions at different stages of pathological process in patients with type 1 diabetes mellitus andmicrogiopathy of different severity. Materials and methods. Comprehensive analysis of parameters of metabolism, hemogram, platelet and plasma hemost...

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Autores principales:	Galina Georgievna Petrik, Svetlana Anatol'evna Pavlishchuk
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2010
Materias:	diabetes mellitus angiopathies risk factors Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/1d2761cb4c9746fe8e644f1226741a24
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spelling	oai:doaj.org-article:1d2761cb4c9746fe8e644f1226741a242021-11-14T09:00:15ZParameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity2072-03512072-037810.14341/2072-0351-5678https://doaj.org/article/1d2761cb4c9746fe8e644f1226741a242010-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5678https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To identify risk factors of macro-microvascular lesions at different stages of pathological process in patients with type 1 diabetes mellitus andmicrogiopathy of different severity. Materials and methods. Comprehensive analysis of parameters of metabolism, hemogram, platelet and plasma hemostasis in 121 patients (67 menand 54 women of mean age 28.2?10.7 years) with type 1 diabetes mellitus and angiopathy of different severity. Results. All patients had hyperglycemia along with dysproteinemia and altered lipid spectrum. Mean platelet volume and aggregation activity increasedwhile activated partial thromboplastic time decreased compared with control subjects regardless of the presence and severity of microangiopathy. Conclusion. Morphological and functional characteristics of platelets and activated partial throm-boplastic time are differently related to metabolicchanges.Galina Georgievna PetrikSvetlana Anatol'evna PavlishchukEndocrinology Research Centrearticlediabetes mellitusangiopathiesrisk factorsNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 2, Pp 75-80 (2010)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus angiopathies risk factors Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus angiopathies risk factors Nutritional diseases. Deficiency diseases RC620-627 Galina Georgievna Petrik Svetlana Anatol'evna Pavlishchuk Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
description	Aim. To identify risk factors of macro-microvascular lesions at different stages of pathological process in patients with type 1 diabetes mellitus andmicrogiopathy of different severity. Materials and methods. Comprehensive analysis of parameters of metabolism, hemogram, platelet and plasma hemostasis in 121 patients (67 menand 54 women of mean age 28.2?10.7 years) with type 1 diabetes mellitus and angiopathy of different severity. Results. All patients had hyperglycemia along with dysproteinemia and altered lipid spectrum. Mean platelet volume and aggregation activity increasedwhile activated partial thromboplastic time decreased compared with control subjects regardless of the presence and severity of microangiopathy. Conclusion. Morphological and functional characteristics of platelets and activated partial throm-boplastic time are differently related to metabolicchanges.
format	article
author	Galina Georgievna Petrik Svetlana Anatol'evna Pavlishchuk
author_facet	Galina Georgievna Petrik Svetlana Anatol'evna Pavlishchuk
author_sort	Galina Georgievna Petrik
title	Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
title_short	Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
title_full	Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
title_fullStr	Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
title_full_unstemmed	Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
title_sort	parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity
publisher	Endocrinology Research Centre
publishDate	2010
url	https://doaj.org/article/1d2761cb4c9746fe8e644f1226741a24
work_keys_str_mv	AT galinageorgievnapetrik parametersofmetabolismandhemostasisinpatientswithtype1diabetesmellitusandmicrogiopathyofdifferentseverity AT svetlanaanatolevnapavlishchuk parametersofmetabolismandhemostasisinpatientswithtype1diabetesmellitusandmicrogiopathyofdifferentseverity
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Parameters of metabolism and hemostasis in patients with type 1 diabetes mellitus and microgiopathy of different severity

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