pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment
Irinotecan (IRN) is a semisynthetic derivative of camptothecin that acts as a topoisomerase I inhibitor. IRN is used worldwide for the treatment of several types of cancer, including colorectal cancer, however its use can lead to serious adverse effects, as diarrhea and myelosuppression. Liposomes a...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Elsevier
2021
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Acceso en línea: | https://doaj.org/article/1d302669881041af945832310c5196dc |
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