Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex

Ilias Georgalas, Alexandros A Rouvas, Dimitrios A Karagiannis, Athanasios I Kotsolis, Ioannis D LadasDepartment of Ophthalmology, Medical School of Athens University, Athens, GreeceAbstract: This is a case report of a 83-year-old man with choroidal neovascularization (CNV), due to age-related macula...

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Autores principales: Ilias Georgalas, Alexandros A Rouvas, Dimitrios A Karagiannis, Athanasios I Kotsolis, Ioannis D Ladas
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Publicado: Dove Medical Press 2008
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spelling oai:doaj.org-article:1d30b2a0906248f4991c90ac95b5f7642021-12-02T01:06:55ZPhotodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex1177-54671177-5483https://doaj.org/article/1d30b2a0906248f4991c90ac95b5f7642008-12-01T00:00:00Zhttp://www.dovepress.com/photodynamic-therapy-of-choroidal-neovascularization-with-enlargement--a2657https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ilias Georgalas, Alexandros A Rouvas, Dimitrios A Karagiannis, Athanasios I Kotsolis, Ioannis D LadasDepartment of Ophthalmology, Medical School of Athens University, Athens, GreeceAbstract: This is a case report of a 83-year-old man with choroidal neovascularization (CNV), due to age-related macular degeneration (AMD) in his right eye. Digital fluorescein (FA) and indocyanine green angiography (ICG) were performed, which disclosed predominantly classic subfoveal CNV and a dilated and tortuous feeding complex. The visual acuity was 20/800. Anti-vascular endothelial growth factor (anti-VEGF) treatment was suggested, however, the patient was not keen to receive an intraocular injection. Modified photodynamic therapy (PDT) with spot size enlarged, to include not only the CNV lesion but the feeding complex as well, was performed. Ten days after one session of PDT, ICG showed absence of leakage from the CNV and complete occlusion of the feeding complex. The visual acuity gradually improved to 20/100 and remained stable during the following 23 months. No evidence of CNV leakage was seen in the FA and ICG during the follow up period. Adjustment of the PDT spot size to include the detectable by ICG feeding complex might be an additional option in order to close the subfoveal CNV and might be considered as an alternative to intravitreal injection of anti-VEGF in selected cases where anti-VEGF treatment is not available.Keywords: age-related macular degeneration, choroidal neovascularization, photodynamic treatment, feeder vessel Ilias GeorgalasAlexandros A RouvasDimitrios A KaragiannisAthanasios I KotsolisIoannis D LadasDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 13-16 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Ilias Georgalas
Alexandros A Rouvas
Dimitrios A Karagiannis
Athanasios I Kotsolis
Ioannis D Ladas
Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
description Ilias Georgalas, Alexandros A Rouvas, Dimitrios A Karagiannis, Athanasios I Kotsolis, Ioannis D LadasDepartment of Ophthalmology, Medical School of Athens University, Athens, GreeceAbstract: This is a case report of a 83-year-old man with choroidal neovascularization (CNV), due to age-related macular degeneration (AMD) in his right eye. Digital fluorescein (FA) and indocyanine green angiography (ICG) were performed, which disclosed predominantly classic subfoveal CNV and a dilated and tortuous feeding complex. The visual acuity was 20/800. Anti-vascular endothelial growth factor (anti-VEGF) treatment was suggested, however, the patient was not keen to receive an intraocular injection. Modified photodynamic therapy (PDT) with spot size enlarged, to include not only the CNV lesion but the feeding complex as well, was performed. Ten days after one session of PDT, ICG showed absence of leakage from the CNV and complete occlusion of the feeding complex. The visual acuity gradually improved to 20/100 and remained stable during the following 23 months. No evidence of CNV leakage was seen in the FA and ICG during the follow up period. Adjustment of the PDT spot size to include the detectable by ICG feeding complex might be an additional option in order to close the subfoveal CNV and might be considered as an alternative to intravitreal injection of anti-VEGF in selected cases where anti-VEGF treatment is not available.Keywords: age-related macular degeneration, choroidal neovascularization, photodynamic treatment, feeder vessel
format article
author Ilias Georgalas
Alexandros A Rouvas
Dimitrios A Karagiannis
Athanasios I Kotsolis
Ioannis D Ladas
author_facet Ilias Georgalas
Alexandros A Rouvas
Dimitrios A Karagiannis
Athanasios I Kotsolis
Ioannis D Ladas
author_sort Ilias Georgalas
title Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
title_short Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
title_full Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
title_fullStr Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
title_full_unstemmed Photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
title_sort photodynamic therapy of choroidal neovascularization with enlargement of the spot size to include the feeding complex
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/1d30b2a0906248f4991c90ac95b5f764
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AT dimitriosakaragiannis photodynamictherapyofchoroidalneovascularizationwithenlargementofthespotsizetoincludethefeedingcomplex
AT athanasiosikotsolis photodynamictherapyofchoroidalneovascularizationwithenlargementofthespotsizetoincludethefeedingcomplex
AT ioannisdladas photodynamictherapyofchoroidalneovascularizationwithenlargementofthespotsizetoincludethefeedingcomplex
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