Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes

Human development provides a roadmap for advancing pluripotent stem cell-based regenerative therapies. Here the authors mapped human skeletogenesis using RNA sequencing on 5 cell types from a single foetal stage as well as chondrocytes at 4 stages in vivo and 2 stages during in vitro differentiation...

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Autores principales:	Gabriel B. Ferguson, Ben Van Handel, Maxwell Bay, Petko Fiziev, Tonis Org, Siyoung Lee, Ruzanna Shkhyan, Nicholas W. Banks, Mila Scheinberg, Ling Wu, Biagio Saitta, Joseph Elphingstone, A. Noelle Larson, Scott M. Riester, April D. Pyle, Nicholas M. Bernthal, Hanna KA Mikkola, Jason Ernst, Andre J. van Wijnen, Michael Bonaguidi, Denis Evseenko
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1d363aed9a4649c2a647c893fe451af6
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spelling	oai:doaj.org-article:1d363aed9a4649c2a647c893fe451af62021-12-02T17:32:17ZMapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes10.1038/s41467-018-05573-y2041-1723https://doaj.org/article/1d363aed9a4649c2a647c893fe451af62018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05573-yhttps://doaj.org/toc/2041-1723Human development provides a roadmap for advancing pluripotent stem cell-based regenerative therapies. Here the authors mapped human skeletogenesis using RNA sequencing on 5 cell types from a single foetal stage as well as chondrocytes at 4 stages in vivo and 2 stages during in vitro differentiation.Gabriel B. FergusonBen Van HandelMaxwell BayPetko FizievTonis OrgSiyoung LeeRuzanna ShkhyanNicholas W. BanksMila ScheinbergLing WuBiagio SaittaJoseph ElphingstoneA. Noelle LarsonScott M. RiesterApril D. PyleNicholas M. BernthalHanna KA MikkolaJason ErnstAndre J. van WijnenMichael BonaguidiDenis EvseenkoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gabriel B. Ferguson Ben Van Handel Maxwell Bay Petko Fiziev Tonis Org Siyoung Lee Ruzanna Shkhyan Nicholas W. Banks Mila Scheinberg Ling Wu Biagio Saitta Joseph Elphingstone A. Noelle Larson Scott M. Riester April D. Pyle Nicholas M. Bernthal Hanna KA Mikkola Jason Ernst Andre J. van Wijnen Michael Bonaguidi Denis Evseenko Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
description	Human development provides a roadmap for advancing pluripotent stem cell-based regenerative therapies. Here the authors mapped human skeletogenesis using RNA sequencing on 5 cell types from a single foetal stage as well as chondrocytes at 4 stages in vivo and 2 stages during in vitro differentiation.
format	article
author	Gabriel B. Ferguson Ben Van Handel Maxwell Bay Petko Fiziev Tonis Org Siyoung Lee Ruzanna Shkhyan Nicholas W. Banks Mila Scheinberg Ling Wu Biagio Saitta Joseph Elphingstone A. Noelle Larson Scott M. Riester April D. Pyle Nicholas M. Bernthal Hanna KA Mikkola Jason Ernst Andre J. van Wijnen Michael Bonaguidi Denis Evseenko
author_facet	Gabriel B. Ferguson Ben Van Handel Maxwell Bay Petko Fiziev Tonis Org Siyoung Lee Ruzanna Shkhyan Nicholas W. Banks Mila Scheinberg Ling Wu Biagio Saitta Joseph Elphingstone A. Noelle Larson Scott M. Riester April D. Pyle Nicholas M. Bernthal Hanna KA Mikkola Jason Ernst Andre J. van Wijnen Michael Bonaguidi Denis Evseenko
author_sort	Gabriel B. Ferguson
title	Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
title_short	Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
title_full	Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
title_fullStr	Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
title_full_unstemmed	Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
title_sort	mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1d363aed9a4649c2a647c893fe451af6
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Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes

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