BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

The BEN-solo proteins—including Insensitive (Insv), Elba1 and Elba2—function in both transcriptional repression and chromatin insulation. Here, the authors investigate the role of these proteins in Drosophila embryos, finding that ELBA and Insv function as general insulators and partition active chr...

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Autores principales:	Malin Ueberschär, Huazhen Wang, Chun Zhang, Shu Kondo, Tsutomu Aoki, Paul Schedl, Eric C. Lai, Jiayu Wen, Qi Dai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1d3734f528d84257b773408e540437b6
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spelling	oai:doaj.org-article:1d3734f528d84257b773408e540437b62021-12-02T17:01:44ZBEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila10.1038/s41467-019-13558-82041-1723https://doaj.org/article/1d3734f528d84257b773408e540437b62019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13558-8https://doaj.org/toc/2041-1723The BEN-solo proteins—including Insensitive (Insv), Elba1 and Elba2—function in both transcriptional repression and chromatin insulation. Here, the authors investigate the role of these proteins in Drosophila embryos, finding that ELBA and Insv function as general insulators and partition active chromatin to ensure proper gene activation in Drosophila.Malin UeberschärHuazhen WangChun ZhangShu KondoTsutomu AokiPaul SchedlEric C. LaiJiayu WenQi DaiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Malin Ueberschär Huazhen Wang Chun Zhang Shu Kondo Tsutomu Aoki Paul Schedl Eric C. Lai Jiayu Wen Qi Dai BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
description	The BEN-solo proteins—including Insensitive (Insv), Elba1 and Elba2—function in both transcriptional repression and chromatin insulation. Here, the authors investigate the role of these proteins in Drosophila embryos, finding that ELBA and Insv function as general insulators and partition active chromatin to ensure proper gene activation in Drosophila.
format	article
author	Malin Ueberschär Huazhen Wang Chun Zhang Shu Kondo Tsutomu Aoki Paul Schedl Eric C. Lai Jiayu Wen Qi Dai
author_facet	Malin Ueberschär Huazhen Wang Chun Zhang Shu Kondo Tsutomu Aoki Paul Schedl Eric C. Lai Jiayu Wen Qi Dai
author_sort	Malin Ueberschär
title	BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
title_short	BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
title_full	BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
title_fullStr	BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
title_full_unstemmed	BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
title_sort	ben-solo factors partition active chromatin to ensure proper gene activation in drosophila
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1d3734f528d84257b773408e540437b6
work_keys_str_mv	AT malinueberschar bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT huazhenwang bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT chunzhang bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT shukondo bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT tsutomuaoki bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT paulschedl bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT ericclai bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT jiayuwen bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila AT qidai bensolofactorspartitionactivechromatintoensurepropergeneactivationindrosophila
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BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

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