BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

The BEN-solo proteins—including Insensitive (Insv), Elba1 and Elba2—function in both transcriptional repression and chromatin insulation. Here, the authors investigate the role of these proteins in Drosophila embryos, finding that ELBA and Insv function as general insulators and partition active chr...

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Autores principales: Malin Ueberschär, Huazhen Wang, Chun Zhang, Shu Kondo, Tsutomu Aoki, Paul Schedl, Eric C. Lai, Jiayu Wen, Qi Dai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1d3734f528d84257b773408e540437b6
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