Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia

Abstract Various forms of supraventricular tachycardia (SVT) occur in patients with severe pulmonary hypertension (PH). Despite the high efficacy of radiofrequency catheter ablation (RFCA) for SVT, insufficient data exist regarding patients with PH. Thirty SVTs in 23 PH patients (age 47 [35–60] year...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hiroyuki Kamada, Junji Kaneyama, Yuko Y. Inoue, Takashi Noda, Nobuhiko Ueda, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Kenichiro Yamagata, Koji Miyamoto, Tatsuo Aoki, Takeshi Ogo, Satoshi Nagase, Takeshi Aiba, Kazuhiro Satomi, Kengo Kusano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1d37e71fa6d7428c99d6a7d4c686cd22
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1d37e71fa6d7428c99d6a7d4c686cd22
record_format	dspace
spelling	oai:doaj.org-article:1d37e71fa6d7428c99d6a7d4c686cd222021-12-02T19:06:29ZLong term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia10.1038/s41598-021-95508-32045-2322https://doaj.org/article/1d37e71fa6d7428c99d6a7d4c686cd222021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95508-3https://doaj.org/toc/2045-2322Abstract Various forms of supraventricular tachycardia (SVT) occur in patients with severe pulmonary hypertension (PH). Despite the high efficacy of radiofrequency catheter ablation (RFCA) for SVT, insufficient data exist regarding patients with PH. Thirty SVTs in 23 PH patients (age 47 [35–60] years; mean pulmonary artery pressure 44 [32–50] mmHg) were analyzed. Procedural success rate, short- and long-term clinical outcomes, were evaluated during a median follow-up of 5.1 years. Single-procedure success rate was 83%; 94% (17/18) in typical atrial flutter, 73% (8/11) in atrial tachycardia (AT), and 100% (1/1) in atrioventricular nodal reentrant tachycardia. Antiarrhythmic drugs, serum brain natriuretic peptide levels and number of hospitalizations significantly decreased after RFCA than that before (p = 0.002, 0.04, and 0.002, respectively). Four patients had several procedures. After last RFCA, 12 patients had SVT and 8 patients died. Kaplan–Meier curves showed that patients with SVT after the last RFCA had a lower survival rate compared to those without (p = 0.0297). Multivariate analysis identified any SVT after the last RFCA as significant risk factor of mortality (hazard ratio: 9.31; p = 0.016). RFCA for SVT in patients with PH is feasible and effective in the short-term, but SVT is common during long-term follow-up and associated with lower survival.Hiroyuki KamadaJunji KaneyamaYuko Y. InoueTakashi NodaNobuhiko UedaKenzaburo NakajimaTsukasa KamakuraMitsuru WadaKohei IshibashiKenichiro YamagataKoji MiyamotoTatsuo AokiTakeshi OgoSatoshi NagaseTakeshi AibaKazuhiro SatomiKengo KusanoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hiroyuki Kamada Junji Kaneyama Yuko Y. Inoue Takashi Noda Nobuhiko Ueda Kenzaburo Nakajima Tsukasa Kamakura Mitsuru Wada Kohei Ishibashi Kenichiro Yamagata Koji Miyamoto Tatsuo Aoki Takeshi Ogo Satoshi Nagase Takeshi Aiba Kazuhiro Satomi Kengo Kusano Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
description	Abstract Various forms of supraventricular tachycardia (SVT) occur in patients with severe pulmonary hypertension (PH). Despite the high efficacy of radiofrequency catheter ablation (RFCA) for SVT, insufficient data exist regarding patients with PH. Thirty SVTs in 23 PH patients (age 47 [35–60] years; mean pulmonary artery pressure 44 [32–50] mmHg) were analyzed. Procedural success rate, short- and long-term clinical outcomes, were evaluated during a median follow-up of 5.1 years. Single-procedure success rate was 83%; 94% (17/18) in typical atrial flutter, 73% (8/11) in atrial tachycardia (AT), and 100% (1/1) in atrioventricular nodal reentrant tachycardia. Antiarrhythmic drugs, serum brain natriuretic peptide levels and number of hospitalizations significantly decreased after RFCA than that before (p = 0.002, 0.04, and 0.002, respectively). Four patients had several procedures. After last RFCA, 12 patients had SVT and 8 patients died. Kaplan–Meier curves showed that patients with SVT after the last RFCA had a lower survival rate compared to those without (p = 0.0297). Multivariate analysis identified any SVT after the last RFCA as significant risk factor of mortality (hazard ratio: 9.31; p = 0.016). RFCA for SVT in patients with PH is feasible and effective in the short-term, but SVT is common during long-term follow-up and associated with lower survival.
format	article
author	Hiroyuki Kamada Junji Kaneyama Yuko Y. Inoue Takashi Noda Nobuhiko Ueda Kenzaburo Nakajima Tsukasa Kamakura Mitsuru Wada Kohei Ishibashi Kenichiro Yamagata Koji Miyamoto Tatsuo Aoki Takeshi Ogo Satoshi Nagase Takeshi Aiba Kazuhiro Satomi Kengo Kusano
author_facet	Hiroyuki Kamada Junji Kaneyama Yuko Y. Inoue Takashi Noda Nobuhiko Ueda Kenzaburo Nakajima Tsukasa Kamakura Mitsuru Wada Kohei Ishibashi Kenichiro Yamagata Koji Miyamoto Tatsuo Aoki Takeshi Ogo Satoshi Nagase Takeshi Aiba Kazuhiro Satomi Kengo Kusano
author_sort	Hiroyuki Kamada
title	Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
title_short	Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
title_full	Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
title_fullStr	Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
title_full_unstemmed	Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
title_sort	long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1d37e71fa6d7428c99d6a7d4c686cd22
work_keys_str_mv	AT hiroyukikamada longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT junjikaneyama longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT yukoyinoue longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT takashinoda longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT nobuhikoueda longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT kenzaburonakajima longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT tsukasakamakura longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT mitsuruwada longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT koheiishibashi longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT kenichiroyamagata longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT kojimiyamoto longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT tatsuoaoki longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT takeshiogo longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT satoshinagase longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT takeshiaiba longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT kazuhirosatomi longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia AT kengokusano longtermprognosisinpatientswithpulmonaryhypertensionundergoingcatheterablationforsupraventriculartachycardia
_version_	1718377134567718912

Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia

Ejemplares similares