Noise reduction facilitated by dosage compensation in gene networks

Cells must function despite the noisiness of their processes by tolerating or reducing such variability. Here, the authors combine experiment and modelling to show that a network motif that mediates network-dosage compensation also reduces noise in network output, suggesting that noise is tuneable.

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Detalles Bibliográficos
Autores principales:	Weilin Peng, Ruijie Song, Murat Acar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1d3ba8f6965c43c297a65e4937514811
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spelling	oai:doaj.org-article:1d3ba8f6965c43c297a65e49375148112021-12-02T17:31:35ZNoise reduction facilitated by dosage compensation in gene networks10.1038/ncomms129592041-1723https://doaj.org/article/1d3ba8f6965c43c297a65e49375148112016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12959https://doaj.org/toc/2041-1723Cells must function despite the noisiness of their processes by tolerating or reducing such variability. Here, the authors combine experiment and modelling to show that a network motif that mediates network-dosage compensation also reduces noise in network output, suggesting that noise is tuneable.Weilin PengRuijie SongMurat AcarNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Weilin Peng Ruijie Song Murat Acar Noise reduction facilitated by dosage compensation in gene networks
description	Cells must function despite the noisiness of their processes by tolerating or reducing such variability. Here, the authors combine experiment and modelling to show that a network motif that mediates network-dosage compensation also reduces noise in network output, suggesting that noise is tuneable.
format	article
author	Weilin Peng Ruijie Song Murat Acar
author_facet	Weilin Peng Ruijie Song Murat Acar
author_sort	Weilin Peng
title	Noise reduction facilitated by dosage compensation in gene networks
title_short	Noise reduction facilitated by dosage compensation in gene networks
title_full	Noise reduction facilitated by dosage compensation in gene networks
title_fullStr	Noise reduction facilitated by dosage compensation in gene networks
title_full_unstemmed	Noise reduction facilitated by dosage compensation in gene networks
title_sort	noise reduction facilitated by dosage compensation in gene networks
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/1d3ba8f6965c43c297a65e4937514811
work_keys_str_mv	AT weilinpeng noisereductionfacilitatedbydosagecompensationingenenetworks AT ruijiesong noisereductionfacilitatedbydosagecompensationingenenetworks AT muratacar noisereductionfacilitatedbydosagecompensationingenenetworks
_version_	1718380537669746688

Noise reduction facilitated by dosage compensation in gene networks

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