Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?

Multiple lines of evidence have shown that elevated blood troponin is strongly associated with poor prognosis in patients with the novel coronavirus disease 2019 (COVID-19). Possible mechanisms of myocardial injury in COVID-19 include ischaemia due to circulatory and respiratory failure, epicardial...

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Autores principales:	Maki Komiyama, Koji Hasegawa, Akira Matsumori
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2020
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/1d41107a58004775ab0cb7621ba45ff1
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spelling	oai:doaj.org-article:1d41107a58004775ab0cb7621ba45ff12021-12-04T16:03:02ZDilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?10.15420/ecr.2020.171758-37641758-3756https://doaj.org/article/1d41107a58004775ab0cb7621ba45ff12020-05-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2020.17https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Multiple lines of evidence have shown that elevated blood troponin is strongly associated with poor prognosis in patients with the novel coronavirus disease 2019 (COVID-19). Possible mechanisms of myocardial injury in COVID-19 include ischaemia due to circulatory and respiratory failure, epicardial or intramyocardial small coronary artery thrombotic obstruction due to increased coagulability, and myocarditis caused by systemic inflammation or direct binding of the virus to its receptor, angiotensin-converting enzyme-2 (ACE2), which is abundantly expressed in the heart. It is postulated that persistent immune activation upon viral infection increases the risk of developing dilated cardiomyopathy in COVID-19 patients.Maki KomiyamaKoji HasegawaAkira MatsumoriRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 15, Iss , Pp - (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Maki Komiyama Koji Hasegawa Akira Matsumori Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
description	Multiple lines of evidence have shown that elevated blood troponin is strongly associated with poor prognosis in patients with the novel coronavirus disease 2019 (COVID-19). Possible mechanisms of myocardial injury in COVID-19 include ischaemia due to circulatory and respiratory failure, epicardial or intramyocardial small coronary artery thrombotic obstruction due to increased coagulability, and myocarditis caused by systemic inflammation or direct binding of the virus to its receptor, angiotensin-converting enzyme-2 (ACE2), which is abundantly expressed in the heart. It is postulated that persistent immune activation upon viral infection increases the risk of developing dilated cardiomyopathy in COVID-19 patients.
format	article
author	Maki Komiyama Koji Hasegawa Akira Matsumori
author_facet	Maki Komiyama Koji Hasegawa Akira Matsumori
author_sort	Maki Komiyama
title	Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
title_short	Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
title_full	Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
title_fullStr	Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
title_full_unstemmed	Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
title_sort	dilated cardiomyopathy risk in patients with coronavirus disease 2019: how to identify and characterise it early?
publisher	Radcliffe Medical Media
publishDate	2020
url	https://doaj.org/article/1d41107a58004775ab0cb7621ba45ff1
work_keys_str_mv	AT makikomiyama dilatedcardiomyopathyriskinpatientswithcoronavirusdisease2019howtoidentifyandcharacteriseitearly AT kojihasegawa dilatedcardiomyopathyriskinpatientswithcoronavirusdisease2019howtoidentifyandcharacteriseitearly AT akiramatsumori dilatedcardiomyopathyriskinpatientswithcoronavirusdisease2019howtoidentifyandcharacteriseitearly
_version_	1718372721171103744

Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?

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