The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method

Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown. Therefore, research related to the use of the lowest concentration...

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Autores principales:	Amal Rezka Putra, Khoirunnisa Fauziah Asyikin, Robertus Dwi Hendarto, Agus Ariyanto, Enny Lestari, Sumandi Juliyanto, Ahsanal Fikri
Formato:	article
Lenguaje:	EN
Publicado:	University of Brawijaya 2021
Materias:	radiochemical purity [153sm]sm-edtmp thin layer chromatography ammonia concentration mobile phase Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/1d414dc28a474b42b7b323d7d14ef37b
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spelling	oai:doaj.org-article:1d414dc28a474b42b7b323d7d14ef37b2021-11-24T11:10:59ZThe Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method2302-46902541-0733https://doaj.org/article/1d414dc28a474b42b7b323d7d14ef37b2021-04-01T00:00:00Zhttps://jpacr.ub.ac.id/index.php/jpacr/article/view/562/pdfhttps://doaj.org/toc/2302-4690https://doaj.org/toc/2541-0733Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown. Therefore, research related to the use of the lowest concentration in the radiochemical purity test of [153Sm]Sm-EDTMP is necessary. This research method includes labelling of EDTMP using Samarium-153, preparation of the mobile phase with variations in the concentration of 25% ammonia: water, radiochemical purity test and data analysis using t-test statistics. The results of this study are the concentration of 25% ammonia: water (1: 9) to (1: 200) still shows good separation with Rf of [153Sm]SmCl3 and [153Sm]Sm-EDTMP at 0.0, 1.0 respectively, whereas with a thinner concentration of ammonia indicates less optimal separation with Rf [153Sm]SmCl3 at 0.35 to 1.0. Comparison of concentrated ammonia concentrations of 1: 9 and dilute 1: 200 was performed using a statistical t-test. The results of the data analysis showed that the two methods were not significantly different, indicated by the t-value of 0.82 less than 2.78. The conclusion of this study is that the lowest concentration of 25% ammonia and water in the radiochemical purity test of [153Sm]Sm-EDTMP is 1: 200.Amal Rezka PutraKhoirunnisa Fauziah AsyikinRobertus Dwi HendartoAgus AriyantoEnny LestariSumandi Juliyanto Ahsanal FikriUniversity of Brawijayaarticleradiochemical purity[153sm]sm-edtmpthin layer chromatographyammonia concentrationmobile phaseChemistryQD1-999ENJournal of Pure and Applied Chemistry Research, Vol 10, Iss 1, Pp 37-43 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	radiochemical purity [153sm]sm-edtmp thin layer chromatography ammonia concentration mobile phase Chemistry QD1-999
spellingShingle	radiochemical purity [153sm]sm-edtmp thin layer chromatography ammonia concentration mobile phase Chemistry QD1-999 Amal Rezka Putra Khoirunnisa Fauziah Asyikin Robertus Dwi Hendarto Agus Ariyanto Enny Lestari Sumandi Juliyanto Ahsanal Fikri The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method
description	Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown. Therefore, research related to the use of the lowest concentration in the radiochemical purity test of [153Sm]Sm-EDTMP is necessary. This research method includes labelling of EDTMP using Samarium-153, preparation of the mobile phase with variations in the concentration of 25% ammonia: water, radiochemical purity test and data analysis using t-test statistics. The results of this study are the concentration of 25% ammonia: water (1: 9) to (1: 200) still shows good separation with Rf of [153Sm]SmCl3 and [153Sm]Sm-EDTMP at 0.0, 1.0 respectively, whereas with a thinner concentration of ammonia indicates less optimal separation with Rf [153Sm]SmCl3 at 0.35 to 1.0. Comparison of concentrated ammonia concentrations of 1: 9 and dilute 1: 200 was performed using a statistical t-test. The results of the data analysis showed that the two methods were not significantly different, indicated by the t-value of 0.82 less than 2.78. The conclusion of this study is that the lowest concentration of 25% ammonia and water in the radiochemical purity test of [153Sm]Sm-EDTMP is 1: 200.
format	article
author	Amal Rezka Putra Khoirunnisa Fauziah Asyikin Robertus Dwi Hendarto Agus Ariyanto Enny Lestari Sumandi Juliyanto Ahsanal Fikri
author_facet	Amal Rezka Putra Khoirunnisa Fauziah Asyikin Robertus Dwi Hendarto Agus Ariyanto Enny Lestari Sumandi Juliyanto Ahsanal Fikri
author_sort	Amal Rezka Putra
title	The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method
title_short	The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method
title_full	The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method
title_fullStr	The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method
title_full_unstemmed	The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method
title_sort	use of low ammonia concentration in the radiochemical purity test of [153sm]sm-edtmp by using the thin layer chromatography method
publisher	University of Brawijaya
publishDate	2021
url	https://doaj.org/article/1d414dc28a474b42b7b323d7d14ef37b
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The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method

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