The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine

Signals mediating tissue-specific control of immune cell fate and function remain largely uncharacterized. Here the authors uncover a requirement of ITK, a kinase mediating TCR signaling, for IL-2-dependent ILC2 cell survival specifically in the intestine.

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Autores principales: Hyoung-Soo Cho, Andrea Reboldi, Jason A. Hall, Leslie J. Berg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1d4279bb99b54c9a90b4d5b38b6101b5
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