Tissue context determines the penetrance of regulatory DNA variation
The functional consequences of variation in human regulatory DNA depend on the local chromatin environment and the cell/tissue context. Here the authors use highly diverged hybrid mice to study genetic effects on DNA accessibility in vivo across multiple cell and tissue types.
Guardado en:
Autores principales: | Jessica M. Halow, Rachel Byron, Megan S. Hogan, Raquel Ordoñez, Mark Groudine, M. A. Bender, John A. Stamatoyannopoulos, Matthew T. Maurano |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1d484e6b9c4d452395c7af6a519b4e6c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Pharmacokinetics and skin-tissue penetration of daptomycin in rats
por: Matsumoto K, et al.
Publicado: (2015) -
Determination of the Permeation and Penetration of Flurbiprofen into Cadaveric Human Pharynx Tissue
por: Turner R, et al.
Publicado: (2020) -
Technological priorities for the development of Russia’s industrial sector in the context of deep digital penetration
por: O. E. Pudovkina
Publicado: (2021) -
Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation
por: Grigorios Georgolopoulos, et al.
Publicado: (2021) -
Ankyrin repeats in context with human population variation.
por: Javier S Utgés, et al.
Publicado: (2021)