A rhesus macaque model of Asian-lineage Zika virus infection

Animal models of infection with Zika virus (ZIKV) are urgently needed for a better understanding of pathogenesis and for testing potential therapies. Here, the authors describe infection of rhesus macaques with an Asian-lineage ZIKV strain as a relevant animal model for studying ZIKV pathogenesis.

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Autores principales: Dawn M. Dudley, Matthew T. Aliota, Emma L. Mohr, Andrea M. Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, Meghan E. Breitbach, Mustafa N. Rasheed, Christina M. Newman, Dane D. Gellerup, Louise H. Moncla, Jennifer Post, Nancy Schultz-Darken, Michele L. Schotzko, Jennifer M. Hayes, Josh A. Eudailey, M. Anthony Moody, Sallie R. Permar, Shelby L. O’Connor, Eva G. Rakasz, Heather A. Simmons, Saverio Capuano, Thaddeus G. Golos, Jorge E. Osorio, Thomas C. Friedrich, David H. O’Connor
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1d500df450f942ebbe6246e44f2a96d7
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spelling oai:doaj.org-article:1d500df450f942ebbe6246e44f2a96d72021-12-02T15:35:43ZA rhesus macaque model of Asian-lineage Zika virus infection10.1038/ncomms122042041-1723https://doaj.org/article/1d500df450f942ebbe6246e44f2a96d72016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms12204https://doaj.org/toc/2041-1723Animal models of infection with Zika virus (ZIKV) are urgently needed for a better understanding of pathogenesis and for testing potential therapies. Here, the authors describe infection of rhesus macaques with an Asian-lineage ZIKV strain as a relevant animal model for studying ZIKV pathogenesis.Dawn M. DudleyMatthew T. AliotaEmma L. MohrAndrea M. WeilerGabrielle Lehrer-BreyKim L. WeisgrauMariel S. MohnsMeghan E. BreitbachMustafa N. RasheedChristina M. NewmanDane D. GellerupLouise H. MonclaJennifer PostNancy Schultz-DarkenMichele L. SchotzkoJennifer M. HayesJosh A. EudaileyM. Anthony MoodySallie R. PermarShelby L. O’ConnorEva G. RakaszHeather A. SimmonsSaverio CapuanoThaddeus G. GolosJorge E. OsorioThomas C. FriedrichDavid H. O’ConnorNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dawn M. Dudley
Matthew T. Aliota
Emma L. Mohr
Andrea M. Weiler
Gabrielle Lehrer-Brey
Kim L. Weisgrau
Mariel S. Mohns
Meghan E. Breitbach
Mustafa N. Rasheed
Christina M. Newman
Dane D. Gellerup
Louise H. Moncla
Jennifer Post
Nancy Schultz-Darken
Michele L. Schotzko
Jennifer M. Hayes
Josh A. Eudailey
M. Anthony Moody
Sallie R. Permar
Shelby L. O’Connor
Eva G. Rakasz
Heather A. Simmons
Saverio Capuano
Thaddeus G. Golos
Jorge E. Osorio
Thomas C. Friedrich
David H. O’Connor
A rhesus macaque model of Asian-lineage Zika virus infection
description Animal models of infection with Zika virus (ZIKV) are urgently needed for a better understanding of pathogenesis and for testing potential therapies. Here, the authors describe infection of rhesus macaques with an Asian-lineage ZIKV strain as a relevant animal model for studying ZIKV pathogenesis.
format article
author Dawn M. Dudley
Matthew T. Aliota
Emma L. Mohr
Andrea M. Weiler
Gabrielle Lehrer-Brey
Kim L. Weisgrau
Mariel S. Mohns
Meghan E. Breitbach
Mustafa N. Rasheed
Christina M. Newman
Dane D. Gellerup
Louise H. Moncla
Jennifer Post
Nancy Schultz-Darken
Michele L. Schotzko
Jennifer M. Hayes
Josh A. Eudailey
M. Anthony Moody
Sallie R. Permar
Shelby L. O’Connor
Eva G. Rakasz
Heather A. Simmons
Saverio Capuano
Thaddeus G. Golos
Jorge E. Osorio
Thomas C. Friedrich
David H. O’Connor
author_facet Dawn M. Dudley
Matthew T. Aliota
Emma L. Mohr
Andrea M. Weiler
Gabrielle Lehrer-Brey
Kim L. Weisgrau
Mariel S. Mohns
Meghan E. Breitbach
Mustafa N. Rasheed
Christina M. Newman
Dane D. Gellerup
Louise H. Moncla
Jennifer Post
Nancy Schultz-Darken
Michele L. Schotzko
Jennifer M. Hayes
Josh A. Eudailey
M. Anthony Moody
Sallie R. Permar
Shelby L. O’Connor
Eva G. Rakasz
Heather A. Simmons
Saverio Capuano
Thaddeus G. Golos
Jorge E. Osorio
Thomas C. Friedrich
David H. O’Connor
author_sort Dawn M. Dudley
title A rhesus macaque model of Asian-lineage Zika virus infection
title_short A rhesus macaque model of Asian-lineage Zika virus infection
title_full A rhesus macaque model of Asian-lineage Zika virus infection
title_fullStr A rhesus macaque model of Asian-lineage Zika virus infection
title_full_unstemmed A rhesus macaque model of Asian-lineage Zika virus infection
title_sort rhesus macaque model of asian-lineage zika virus infection
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1d500df450f942ebbe6246e44f2a96d7
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