NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation

NMDARs and MAGUK proteins are capable of forming higher-order protein assemblies, however their organisation in the intact brain is unclear. Here, Frank et al. identify mouse and human supercomplexes and discover their mechanism of assembly using genetic tagging and affinity purification.

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Auteurs principaux: René A. W. Frank, Noboru H. Komiyama, Tomás J. Ryan, Fei Zhu, Thomas J. O’Dell, Seth G. N. Grant
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/1d59b48eca8c4a3bbdb4c8ba16338986
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