The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis

Chlamydia trachomatis does not possess TrpL-mediated transcription attenuation of its trp operon. Here, the authors show that an iron-dependent regulator, YtgR, acts as a tryptophan-dependent attenuator of the trp operon in this organism, due to translational regulation of YtgR levels via a triple t...

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Autores principales:	Nick D. Pokorzynski, Nathan D. Hatch, Scot P. Ouellette, Rey A. Carabeo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1d61775e0be44d8a805cabbaa95c91c5
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spelling	oai:doaj.org-article:1d61775e0be44d8a805cabbaa95c91c52021-12-02T13:57:22ZThe iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis10.1038/s41467-020-20181-52041-1723https://doaj.org/article/1d61775e0be44d8a805cabbaa95c91c52020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20181-5https://doaj.org/toc/2041-1723Chlamydia trachomatis does not possess TrpL-mediated transcription attenuation of its trp operon. Here, the authors show that an iron-dependent regulator, YtgR, acts as a tryptophan-dependent attenuator of the trp operon in this organism, due to translational regulation of YtgR levels via a triple tryptophan motif.Nick D. PokorzynskiNathan D. HatchScot P. OuelletteRey A. CarabeoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nick D. Pokorzynski Nathan D. Hatch Scot P. Ouellette Rey A. Carabeo The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis
description	Chlamydia trachomatis does not possess TrpL-mediated transcription attenuation of its trp operon. Here, the authors show that an iron-dependent regulator, YtgR, acts as a tryptophan-dependent attenuator of the trp operon in this organism, due to translational regulation of YtgR levels via a triple tryptophan motif.
format	article
author	Nick D. Pokorzynski Nathan D. Hatch Scot P. Ouellette Rey A. Carabeo
author_facet	Nick D. Pokorzynski Nathan D. Hatch Scot P. Ouellette Rey A. Carabeo
author_sort	Nick D. Pokorzynski
title	The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis
title_short	The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis
title_full	The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis
title_fullStr	The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis
title_full_unstemmed	The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis
title_sort	iron-dependent repressor ytgr is a tryptophan-dependent attenuator of the trprba operon in chlamydia trachomatis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1d61775e0be44d8a805cabbaa95c91c5
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The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis

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