Moss enables high sensitivity single-nucleotide variant calling from multiple bulk DNA tumor samples

The study of tumour heterogeneity can be improved by sequencing multiple samples, but currently available variant callers have not been tailored to integrate them. Here the authors present Moss, a tool that can leverage multiple samples to improve somatic variant calling in different cancers.

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Detalles Bibliográficos
Autores principales: Chuanyi Zhang, Mohammed El-Kebir, Idoia Ochoa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/1d662e56843240cb8dc1f2695a9295ee
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