Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines

Vaccination is the most effective means of preventing infectious diseases and saving lives. Modern biotechnology largely enabled vaccine development. In the meantime, recent advances in pharmaceutical technology have resulted in the emergence of nanoparticles that are extensively investigated as pro...

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Autores principales:	Mohamed Ahmed Attia, Ebtessam Ahmed Essa, Toka Tarek Elebyary, Ahmed Mostafa Faheem, Amal Ali Elkordy
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	nanoparticles SARS-CoV adjuvants liposomes vaccines Medicine R Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/1d6d89deaf3844e0a6e996e462cd7c9f
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spelling	oai:doaj.org-article:1d6d89deaf3844e0a6e996e462cd7c9f2021-11-25T18:39:55ZBrief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines10.3390/ph141111731424-8247https://doaj.org/article/1d6d89deaf3844e0a6e996e462cd7c9f2021-11-01T00:00:00Zhttps://www.mdpi.com/1424-8247/14/11/1173https://doaj.org/toc/1424-8247Vaccination is the most effective means of preventing infectious diseases and saving lives. Modern biotechnology largely enabled vaccine development. In the meantime, recent advances in pharmaceutical technology have resulted in the emergence of nanoparticles that are extensively investigated as promising miniaturized drug delivery systems. Scientists are particularly interested in liposomes as an important carrier for vaccine development. Wide acceptability of liposomes lies in their flexibility and versatility. Due to their unique vesicular structure with alternating aqueous and lipid compartments, liposomes can enclose both hydrophilic and lipophilic compounds, including antigens. Liposome composition can be tailored to obtain the desired immune response and adjuvant characteristics. During the current pandemic of COVID-19, many liposome-based vaccines have been developed with great success. This review covers a liposome-based vaccine designed particularly to combat viral infection of the lower respiratory tract (LRT), i.e., infection of the lung, specifically in the lower airways. Viruses such as influenza, respiratory syncytial virus (RSV), severe acute respiratory syndrome (SARS-CoV-1 and SARS-CoV-2) are common causes of LRT infections, hence this review mainly focuses on this category of viruses.Mohamed Ahmed AttiaEbtessam Ahmed EssaToka Tarek ElebyaryAhmed Mostafa FaheemAmal Ali ElkordyMDPI AGarticlenanoparticlesSARS-CoVadjuvantsliposomesvaccinesMedicineRPharmacy and materia medicaRS1-441ENPharmaceuticals, Vol 14, Iss 1173, p 1173 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nanoparticles SARS-CoV adjuvants liposomes vaccines Medicine R Pharmacy and materia medica RS1-441
spellingShingle	nanoparticles SARS-CoV adjuvants liposomes vaccines Medicine R Pharmacy and materia medica RS1-441 Mohamed Ahmed Attia Ebtessam Ahmed Essa Toka Tarek Elebyary Ahmed Mostafa Faheem Amal Ali Elkordy Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
description	Vaccination is the most effective means of preventing infectious diseases and saving lives. Modern biotechnology largely enabled vaccine development. In the meantime, recent advances in pharmaceutical technology have resulted in the emergence of nanoparticles that are extensively investigated as promising miniaturized drug delivery systems. Scientists are particularly interested in liposomes as an important carrier for vaccine development. Wide acceptability of liposomes lies in their flexibility and versatility. Due to their unique vesicular structure with alternating aqueous and lipid compartments, liposomes can enclose both hydrophilic and lipophilic compounds, including antigens. Liposome composition can be tailored to obtain the desired immune response and adjuvant characteristics. During the current pandemic of COVID-19, many liposome-based vaccines have been developed with great success. This review covers a liposome-based vaccine designed particularly to combat viral infection of the lower respiratory tract (LRT), i.e., infection of the lung, specifically in the lower airways. Viruses such as influenza, respiratory syncytial virus (RSV), severe acute respiratory syndrome (SARS-CoV-1 and SARS-CoV-2) are common causes of LRT infections, hence this review mainly focuses on this category of viruses.
format	article
author	Mohamed Ahmed Attia Ebtessam Ahmed Essa Toka Tarek Elebyary Ahmed Mostafa Faheem Amal Ali Elkordy
author_facet	Mohamed Ahmed Attia Ebtessam Ahmed Essa Toka Tarek Elebyary Ahmed Mostafa Faheem Amal Ali Elkordy
author_sort	Mohamed Ahmed Attia
title	Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
title_short	Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
title_full	Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
title_fullStr	Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
title_full_unstemmed	Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
title_sort	brief on recent application of liposomal vaccines for lower respiratory tract viral infections: from influenza to covid-19 vaccines
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/1d6d89deaf3844e0a6e996e462cd7c9f
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Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines

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