Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy arising from germinal center or post-germinal center B-cells that retain many of the properties of normal B-cells. Here we show that a subset of DLBCL express the cytokine IL-10 and its receptor. The genetic ablation of IL-10 receptor...

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Autores principales: Kristin Stirm, Peter Leary, Katrin Bertram, Nicolás Gonzalo Núñez, Daria Wüst, Christophe Boudesco, Els Verhoeyen, Thorsten Zenz, Burkhard Becher, Thomas Menter, Alexandar Tzankov, Anne Müller
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
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Acceso en línea:https://doaj.org/article/1d829b2258f141b2b3b452c988a05534
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