Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

Exon junction complexes (EJCs) that mark untranslated mRNA are involved in transport, translation and nonsense-mediated mRNA decay. Here the authors show centrosomal localization of EJCs which appears to be required for both the localization of NIN mRNA around centrosomes and ciliogenesis.

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Autores principales: Oh Sung Kwon, Rahul Mishra, Adham Safieddine, Emeline Coleno, Quentin Alasseur, Marion Faucourt, Isabelle Barbosa, Edouard Bertrand, Nathalie Spassky, Hervé Le Hir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1d82ac1f9eec446e9d08f2e30f0c1cab
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spelling oai:doaj.org-article:1d82ac1f9eec446e9d08f2e30f0c1cab2021-12-02T13:32:51ZExon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis10.1038/s41467-021-21590-w2041-1723https://doaj.org/article/1d82ac1f9eec446e9d08f2e30f0c1cab2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21590-whttps://doaj.org/toc/2041-1723Exon junction complexes (EJCs) that mark untranslated mRNA are involved in transport, translation and nonsense-mediated mRNA decay. Here the authors show centrosomal localization of EJCs which appears to be required for both the localization of NIN mRNA around centrosomes and ciliogenesis.Oh Sung KwonRahul MishraAdham SafieddineEmeline ColenoQuentin AlasseurMarion FaucourtIsabelle BarbosaEdouard BertrandNathalie SpasskyHervé Le HirNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Oh Sung Kwon
Rahul Mishra
Adham Safieddine
Emeline Coleno
Quentin Alasseur
Marion Faucourt
Isabelle Barbosa
Edouard Bertrand
Nathalie Spassky
Hervé Le Hir
Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
description Exon junction complexes (EJCs) that mark untranslated mRNA are involved in transport, translation and nonsense-mediated mRNA decay. Here the authors show centrosomal localization of EJCs which appears to be required for both the localization of NIN mRNA around centrosomes and ciliogenesis.
format article
author Oh Sung Kwon
Rahul Mishra
Adham Safieddine
Emeline Coleno
Quentin Alasseur
Marion Faucourt
Isabelle Barbosa
Edouard Bertrand
Nathalie Spassky
Hervé Le Hir
author_facet Oh Sung Kwon
Rahul Mishra
Adham Safieddine
Emeline Coleno
Quentin Alasseur
Marion Faucourt
Isabelle Barbosa
Edouard Bertrand
Nathalie Spassky
Hervé Le Hir
author_sort Oh Sung Kwon
title Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
title_short Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
title_full Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
title_fullStr Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
title_full_unstemmed Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
title_sort exon junction complex dependent mrna localization is linked to centrosome organization during ciliogenesis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1d82ac1f9eec446e9d08f2e30f0c1cab
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AT rahulmishra exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT adhamsafieddine exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT emelinecoleno exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT quentinalasseur exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT marionfaucourt exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT isabellebarbosa exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT edouardbertrand exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
AT nathaliespassky exonjunctioncomplexdependentmrnalocalizationislinkedtocentrosomeorganizationduringciliogenesis
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