Prdm8 regulates the morphological transition at multipolar phase during neocortical development.

Here, we found that the PR domain protein Prdm8 serves as a key regulator of the length of the multipolar phase by controlling the timing of morphological transition. We used a mouse line with expression of Prdm8-mVenus reporter and found that Prdm8 is predominantly expressed in the middle and upper...

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Autores principales: Mayuko Inoue, Takao Kuroda, Aya Honda, Mariko Komabayashi-Suzuki, Tae Komai, Yoichi Shinkai, Ken-ichi Mizutani
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/1d90a49a62f847ca8b6fbf57d8cfe8dd
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