Efferent feedback controls bilateral auditory spontaneous activity

Spontaneous activity generated in the cochleae propagates into the central auditory system to promote circuit formation before hearing onset. Here, the authors reveal the important role of cholinergic efferent modulation in coordinating bilateral spontaneous activity and the emergence of functional...

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Autores principales: Yixiang Wang, Maya Sanghvi, Alexandra Gribizis, Yueyi Zhang, Lei Song, Barbara Morley, Daniel G. Barson, Joseph Santos-Sacchi, Dhasakumar Navaratnam, Michael Crair
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1d9584c0e1d14575bb5ae26c3aa71dde
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spelling oai:doaj.org-article:1d9584c0e1d14575bb5ae26c3aa71dde2021-12-02T13:41:42ZEfferent feedback controls bilateral auditory spontaneous activity10.1038/s41467-021-22796-82041-1723https://doaj.org/article/1d9584c0e1d14575bb5ae26c3aa71dde2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22796-8https://doaj.org/toc/2041-1723Spontaneous activity generated in the cochleae propagates into the central auditory system to promote circuit formation before hearing onset. Here, the authors reveal the important role of cholinergic efferent modulation in coordinating bilateral spontaneous activity and the emergence of functional responses.Yixiang WangMaya SanghviAlexandra GribizisYueyi ZhangLei SongBarbara MorleyDaniel G. BarsonJoseph Santos-SacchiDhasakumar NavaratnamMichael CrairNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yixiang Wang
Maya Sanghvi
Alexandra Gribizis
Yueyi Zhang
Lei Song
Barbara Morley
Daniel G. Barson
Joseph Santos-Sacchi
Dhasakumar Navaratnam
Michael Crair
Efferent feedback controls bilateral auditory spontaneous activity
description Spontaneous activity generated in the cochleae propagates into the central auditory system to promote circuit formation before hearing onset. Here, the authors reveal the important role of cholinergic efferent modulation in coordinating bilateral spontaneous activity and the emergence of functional responses.
format article
author Yixiang Wang
Maya Sanghvi
Alexandra Gribizis
Yueyi Zhang
Lei Song
Barbara Morley
Daniel G. Barson
Joseph Santos-Sacchi
Dhasakumar Navaratnam
Michael Crair
author_facet Yixiang Wang
Maya Sanghvi
Alexandra Gribizis
Yueyi Zhang
Lei Song
Barbara Morley
Daniel G. Barson
Joseph Santos-Sacchi
Dhasakumar Navaratnam
Michael Crair
author_sort Yixiang Wang
title Efferent feedback controls bilateral auditory spontaneous activity
title_short Efferent feedback controls bilateral auditory spontaneous activity
title_full Efferent feedback controls bilateral auditory spontaneous activity
title_fullStr Efferent feedback controls bilateral auditory spontaneous activity
title_full_unstemmed Efferent feedback controls bilateral auditory spontaneous activity
title_sort efferent feedback controls bilateral auditory spontaneous activity
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1d9584c0e1d14575bb5ae26c3aa71dde
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