One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia

Aliphatic α,ω-dicarboxylic acids (DCAs) are widely used chemicals that are synthesised by multistage chemical oxidations. Here, the authors report an artificially designed biocatalytic cascade for the oxidation of cycloalkanes or cycloalkanols to DCAs in the form of microbial consortia, composed of...

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Autores principales:	Fei Wang, Jing Zhao, Qian Li, Jun Yang, Renjie Li, Jian Min, Xiaojuan Yu, Gao-Wei Zheng, Hui-Lei Yu, Chao Zhai, Carlos G. Acevedo-Rocha, Lixin Ma, Aitao Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1d9a5decd7184485b2f19344448a1971
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spelling	oai:doaj.org-article:1d9a5decd7184485b2f19344448a19712021-12-02T18:37:17ZOne-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia10.1038/s41467-020-18833-72041-1723https://doaj.org/article/1d9a5decd7184485b2f19344448a19712020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18833-7https://doaj.org/toc/2041-1723Aliphatic α,ω-dicarboxylic acids (DCAs) are widely used chemicals that are synthesised by multistage chemical oxidations. Here, the authors report an artificially designed biocatalytic cascade for the oxidation of cycloalkanes or cycloalkanols to DCAs in the form of microbial consortia, composed of three Escherichia coli cell modules.Fei WangJing ZhaoQian LiJun YangRenjie LiJian MinXiaojuan YuGao-Wei ZhengHui-Lei YuChao ZhaiCarlos G. Acevedo-RochaLixin MaAitao LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fei Wang Jing Zhao Qian Li Jun Yang Renjie Li Jian Min Xiaojuan Yu Gao-Wei Zheng Hui-Lei Yu Chao Zhai Carlos G. Acevedo-Rocha Lixin Ma Aitao Li One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
description	Aliphatic α,ω-dicarboxylic acids (DCAs) are widely used chemicals that are synthesised by multistage chemical oxidations. Here, the authors report an artificially designed biocatalytic cascade for the oxidation of cycloalkanes or cycloalkanols to DCAs in the form of microbial consortia, composed of three Escherichia coli cell modules.
format	article
author	Fei Wang Jing Zhao Qian Li Jun Yang Renjie Li Jian Min Xiaojuan Yu Gao-Wei Zheng Hui-Lei Yu Chao Zhai Carlos G. Acevedo-Rocha Lixin Ma Aitao Li
author_facet	Fei Wang Jing Zhao Qian Li Jun Yang Renjie Li Jian Min Xiaojuan Yu Gao-Wei Zheng Hui-Lei Yu Chao Zhai Carlos G. Acevedo-Rocha Lixin Ma Aitao Li
author_sort	Fei Wang
title	One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
title_short	One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
title_full	One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
title_fullStr	One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
title_full_unstemmed	One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
title_sort	one-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed escherichia coli consortia
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1d9a5decd7184485b2f19344448a1971
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One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia

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