High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast

Ribosome biogenesis is a dynamic process that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrangements. Here the authors apply ChemModSeq, a high-throughput RNA structure probing method, to quantitatively measure changes in RNA flexibility during the nucleolar s...

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Autores principales:	Elena Burlacu, Fredrik Lackmann, Lisbeth-Carolina Aguilar, Sergey Belikov, Rob van Nues, Christian Trahan, Ralph D. Hector, Nicholas Dominelli-Whiteley, Scott L. Cockroft, Lars Wieslander, Marlene Oeffinger, Sander Granneman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1da14d21505f4421859e388161a68673
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spelling	oai:doaj.org-article:1da14d21505f4421859e388161a686732021-12-02T15:37:05ZHigh-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast10.1038/s41467-017-00761-82041-1723https://doaj.org/article/1da14d21505f4421859e388161a686732017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00761-8https://doaj.org/toc/2041-1723Ribosome biogenesis is a dynamic process that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrangements. Here the authors apply ChemModSeq, a high-throughput RNA structure probing method, to quantitatively measure changes in RNA flexibility during the nucleolar stages of 60S assembly in yeast.Elena BurlacuFredrik LackmannLisbeth-Carolina AguilarSergey BelikovRob van NuesChristian TrahanRalph D. HectorNicholas Dominelli-WhiteleyScott L. CockroftLars WieslanderMarlene OeffingerSander GrannemanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elena Burlacu Fredrik Lackmann Lisbeth-Carolina Aguilar Sergey Belikov Rob van Nues Christian Trahan Ralph D. Hector Nicholas Dominelli-Whiteley Scott L. Cockroft Lars Wieslander Marlene Oeffinger Sander Granneman High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
description	Ribosome biogenesis is a dynamic process that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrangements. Here the authors apply ChemModSeq, a high-throughput RNA structure probing method, to quantitatively measure changes in RNA flexibility during the nucleolar stages of 60S assembly in yeast.
format	article
author	Elena Burlacu Fredrik Lackmann Lisbeth-Carolina Aguilar Sergey Belikov Rob van Nues Christian Trahan Ralph D. Hector Nicholas Dominelli-Whiteley Scott L. Cockroft Lars Wieslander Marlene Oeffinger Sander Granneman
author_facet	Elena Burlacu Fredrik Lackmann Lisbeth-Carolina Aguilar Sergey Belikov Rob van Nues Christian Trahan Ralph D. Hector Nicholas Dominelli-Whiteley Scott L. Cockroft Lars Wieslander Marlene Oeffinger Sander Granneman
author_sort	Elena Burlacu
title	High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
title_short	High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
title_full	High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
title_fullStr	High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
title_full_unstemmed	High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
title_sort	high-throughput rna structure probing reveals critical folding events during early 60s ribosome assembly in yeast
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1da14d21505f4421859e388161a68673
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High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast

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