qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing

Measuring relative frequencies of DNA double-strand breaks between loci does not provide the full physiological relevance of those breaks. Here Rowicka and colleagues present qDSB-Seq method which uses spike-in double-strand breaks induced by a restriction enzyme to accurately quantify DNA damage.

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Autores principales:	Yingjie Zhu, Anna Biernacka, Benjamin Pardo, Norbert Dojer, Romain Forey, Magdalena Skrzypczak, Bernard Fongang, Jules Nde, Razie Yousefi, Philippe Pasero, Krzysztof Ginalski, Maga Rowicka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1da150c75932433b96bb662db60a6ecc
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spelling	oai:doaj.org-article:1da150c75932433b96bb662db60a6ecc2021-12-02T17:01:52ZqDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing10.1038/s41467-019-10332-82041-1723https://doaj.org/article/1da150c75932433b96bb662db60a6ecc2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10332-8https://doaj.org/toc/2041-1723Measuring relative frequencies of DNA double-strand breaks between loci does not provide the full physiological relevance of those breaks. Here Rowicka and colleagues present qDSB-Seq method which uses spike-in double-strand breaks induced by a restriction enzyme to accurately quantify DNA damage.Yingjie ZhuAnna BiernackaBenjamin PardoNorbert DojerRomain ForeyMagdalena SkrzypczakBernard FongangJules NdeRazie YousefiPhilippe PaseroKrzysztof GinalskiMaga RowickaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yingjie Zhu Anna Biernacka Benjamin Pardo Norbert Dojer Romain Forey Magdalena Skrzypczak Bernard Fongang Jules Nde Razie Yousefi Philippe Pasero Krzysztof Ginalski Maga Rowicka qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
description	Measuring relative frequencies of DNA double-strand breaks between loci does not provide the full physiological relevance of those breaks. Here Rowicka and colleagues present qDSB-Seq method which uses spike-in double-strand breaks induced by a restriction enzyme to accurately quantify DNA damage.
format	article
author	Yingjie Zhu Anna Biernacka Benjamin Pardo Norbert Dojer Romain Forey Magdalena Skrzypczak Bernard Fongang Jules Nde Razie Yousefi Philippe Pasero Krzysztof Ginalski Maga Rowicka
author_facet	Yingjie Zhu Anna Biernacka Benjamin Pardo Norbert Dojer Romain Forey Magdalena Skrzypczak Bernard Fongang Jules Nde Razie Yousefi Philippe Pasero Krzysztof Ginalski Maga Rowicka
author_sort	Yingjie Zhu
title	qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
title_short	qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
title_full	qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
title_fullStr	qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
title_full_unstemmed	qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
title_sort	qdsb-seq is a general method for genome-wide quantification of dna double-strand breaks using sequencing
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1da150c75932433b96bb662db60a6ecc
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qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing

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