Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments

Here, the authors isolate over 800 RSV F-specific antibodies from paired nasopharyngeal tonsil and peripheral blood samples from four young children undergoing adenoidectomy and find that adenoid derived antibodies have overall higher binding affinities and neutralization potencies.

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Autores principales:	Laila Shehata, Wendy F. Wieland-Alter, Daniel P. Maurer, Eunice Chen, Ruth I. Connor, Peter F. Wright, Laura M. Walker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1da6d833061f4c06bafee6e295230c07
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spelling	oai:doaj.org-article:1da6d833061f4c06bafee6e295230c072021-12-02T14:39:20ZSystematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments10.1038/s41467-019-09085-12041-1723https://doaj.org/article/1da6d833061f4c06bafee6e295230c072019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09085-1https://doaj.org/toc/2041-1723Here, the authors isolate over 800 RSV F-specific antibodies from paired nasopharyngeal tonsil and peripheral blood samples from four young children undergoing adenoidectomy and find that adenoid derived antibodies have overall higher binding affinities and neutralization potencies.Laila ShehataWendy F. Wieland-AlterDaniel P. MaurerEunice ChenRuth I. ConnorPeter F. WrightLaura M. WalkerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laila Shehata Wendy F. Wieland-Alter Daniel P. Maurer Eunice Chen Ruth I. Connor Peter F. Wright Laura M. Walker Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments
description	Here, the authors isolate over 800 RSV F-specific antibodies from paired nasopharyngeal tonsil and peripheral blood samples from four young children undergoing adenoidectomy and find that adenoid derived antibodies have overall higher binding affinities and neutralization potencies.
format	article
author	Laila Shehata Wendy F. Wieland-Alter Daniel P. Maurer Eunice Chen Ruth I. Connor Peter F. Wright Laura M. Walker
author_facet	Laila Shehata Wendy F. Wieland-Alter Daniel P. Maurer Eunice Chen Ruth I. Connor Peter F. Wright Laura M. Walker
author_sort	Laila Shehata
title	Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments
title_short	Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments
title_full	Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments
title_fullStr	Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments
title_full_unstemmed	Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments
title_sort	systematic comparison of respiratory syncytial virus-induced memory b cell responses in two anatomical compartments
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1da6d833061f4c06bafee6e295230c07
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Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments

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