Solvation-Guided Design of Fluorescent Probes for Discrimination of Amyloids

Abstract The deposition of insoluble protein aggregates in the brain is a hallmark of many neurodegenerative diseases. While their exact role in neurodegeneration remains unclear, the presence of these amyloid deposits often precedes clinical symptoms. As a result, recent progress in imaging methods...

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Autores principales: Kevin J. Cao, Kristyna M. Elbel, Jessica L. Cifelli, Jordi Cirera, Christina J. Sigurdson, Francesco Paesani, Emmanuel A. Theodorakis, Jerry Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1da911951350412fa1fd1e0d6610d4fc
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