Solvation-Guided Design of Fluorescent Probes for Discrimination of Amyloids
Abstract The deposition of insoluble protein aggregates in the brain is a hallmark of many neurodegenerative diseases. While their exact role in neurodegeneration remains unclear, the presence of these amyloid deposits often precedes clinical symptoms. As a result, recent progress in imaging methods...
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Autores principales: | Kevin J. Cao, Kristyna M. Elbel, Jessica L. Cifelli, Jordi Cirera, Christina J. Sigurdson, Francesco Paesani, Emmanuel A. Theodorakis, Jerry Yang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/1da911951350412fa1fd1e0d6610d4fc |
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