Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions

Cells contain isolated compartments where cascade enzymatic biochemical reactions occur to form essential biological products with high efficiency. Here the authors produce functional hydrogel particles with multiple compartments via microfluidics that contain spatially immobilized natural enzymes i...

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Autores principales: Hongliang Tan, Song Guo, Ngoc-Duy Dinh, Rongcong Luo, Lin Jin, Chia-Hung Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1daf49c724184f3aac023a53cb359ed8
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spelling oai:doaj.org-article:1daf49c724184f3aac023a53cb359ed82021-12-02T14:40:59ZHeterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions10.1038/s41467-017-00757-42041-1723https://doaj.org/article/1daf49c724184f3aac023a53cb359ed82017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00757-4https://doaj.org/toc/2041-1723Cells contain isolated compartments where cascade enzymatic biochemical reactions occur to form essential biological products with high efficiency. Here the authors produce functional hydrogel particles with multiple compartments via microfluidics that contain spatially immobilized natural enzymes in distinct domains for one-pot, tandem reactions.Hongliang TanSong GuoNgoc-Duy DinhRongcong LuoLin JinChia-Hung ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hongliang Tan
Song Guo
Ngoc-Duy Dinh
Rongcong Luo
Lin Jin
Chia-Hung Chen
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
description Cells contain isolated compartments where cascade enzymatic biochemical reactions occur to form essential biological products with high efficiency. Here the authors produce functional hydrogel particles with multiple compartments via microfluidics that contain spatially immobilized natural enzymes in distinct domains for one-pot, tandem reactions.
format article
author Hongliang Tan
Song Guo
Ngoc-Duy Dinh
Rongcong Luo
Lin Jin
Chia-Hung Chen
author_facet Hongliang Tan
Song Guo
Ngoc-Duy Dinh
Rongcong Luo
Lin Jin
Chia-Hung Chen
author_sort Hongliang Tan
title Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
title_short Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
title_full Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
title_fullStr Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
title_full_unstemmed Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
title_sort heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/1daf49c724184f3aac023a53cb359ed8
work_keys_str_mv AT hongliangtan heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions
AT songguo heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions
AT ngocduydinh heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions
AT rongcongluo heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions
AT linjin heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions
AT chiahungchen heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions
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