Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions
Cells contain isolated compartments where cascade enzymatic biochemical reactions occur to form essential biological products with high efficiency. Here the authors produce functional hydrogel particles with multiple compartments via microfluidics that contain spatially immobilized natural enzymes i...
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Nature Portfolio
2017
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oai:doaj.org-article:1daf49c724184f3aac023a53cb359ed82021-12-02T14:40:59ZHeterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions10.1038/s41467-017-00757-42041-1723https://doaj.org/article/1daf49c724184f3aac023a53cb359ed82017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00757-4https://doaj.org/toc/2041-1723Cells contain isolated compartments where cascade enzymatic biochemical reactions occur to form essential biological products with high efficiency. Here the authors produce functional hydrogel particles with multiple compartments via microfluidics that contain spatially immobilized natural enzymes in distinct domains for one-pot, tandem reactions.Hongliang TanSong GuoNgoc-Duy DinhRongcong LuoLin JinChia-Hung ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
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Science Q Hongliang Tan Song Guo Ngoc-Duy Dinh Rongcong Luo Lin Jin Chia-Hung Chen Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
description |
Cells contain isolated compartments where cascade enzymatic biochemical reactions occur to form essential biological products with high efficiency. Here the authors produce functional hydrogel particles with multiple compartments via microfluidics that contain spatially immobilized natural enzymes in distinct domains for one-pot, tandem reactions. |
format |
article |
author |
Hongliang Tan Song Guo Ngoc-Duy Dinh Rongcong Luo Lin Jin Chia-Hung Chen |
author_facet |
Hongliang Tan Song Guo Ngoc-Duy Dinh Rongcong Luo Lin Jin Chia-Hung Chen |
author_sort |
Hongliang Tan |
title |
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
title_short |
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
title_full |
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
title_fullStr |
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
title_full_unstemmed |
Heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
title_sort |
heterogeneous multi-compartmental hydrogel particles as synthetic cells for incompatible tandem reactions |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/1daf49c724184f3aac023a53cb359ed8 |
work_keys_str_mv |
AT hongliangtan heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions AT songguo heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions AT ngocduydinh heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions AT rongcongluo heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions AT linjin heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions AT chiahungchen heterogeneousmulticompartmentalhydrogelparticlesassyntheticcellsforincompatibletandemreactions |
_version_ |
1718390039319150592 |