IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES

Abstract. The article deals with biological issues of obesity, a global epidemic of XXI century. Adipose tissue is considered not only an energy-storage tissue, but as an endocrine organ as well which secretes a variety of bioactive substances (adipokines) including tumor necrosis factor (TNF)-α, in...

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Autores principales:	A. F. Salikhova, L. M. Farkhutdinova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	obesity interleukin-6 immunoglobulins insulin resistance Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/1db85244b911426f8fb6bad472456db5
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spelling	oai:doaj.org-article:1db85244b911426f8fb6bad472456db52021-11-18T08:03:43ZIMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES1563-06252313-741X10.15789/1563-0625-2013-5-465-470https://doaj.org/article/1db85244b911426f8fb6bad472456db52014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/663https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The article deals with biological issues of obesity, a global epidemic of XXI century. Adipose tissue is considered not only an energy-storage tissue, but as an endocrine organ as well which secretes a variety of bioactive substances (adipokines) including tumor necrosis factor (TNF)-α, interleukin-6 (IL-6). Cardiovascular diseases represent the main cause of morbidity and mortality in persons with excessive weight and obese patients. Atherosclerotic lesions represent a pathological substrate of these illnesses. The aim of our study was to analyze corelations between some specific adipocytokines (such as leptine) and some nonspecific cytokines (such as IL-6, TNFα) with indicators of lipid and carbohydrate metabolism. The study group included 123 persons (100 subjects with overweight and obesity, 23 persons with normal weight).The article present results of studying immune parameters of patients with obesity, including cytokine levels, major classes of immunoglobulins, lymphocyte subpopulations in blood serum, and their interrelations with disturbances of carbohydrate and fat metabolism.A. F. SalikhovaL. M. FarkhutdinovaSPb RAACIarticleobesityinterleukin-6immunoglobulinsinsulin resistanceImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 5, Pp 465-470 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	obesity interleukin-6 immunoglobulins insulin resistance Immunologic diseases. Allergy RC581-607
spellingShingle	obesity interleukin-6 immunoglobulins insulin resistance Immunologic diseases. Allergy RC581-607 A. F. Salikhova L. M. Farkhutdinova IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES
description	Abstract. The article deals with biological issues of obesity, a global epidemic of XXI century. Adipose tissue is considered not only an energy-storage tissue, but as an endocrine organ as well which secretes a variety of bioactive substances (adipokines) including tumor necrosis factor (TNF)-α, interleukin-6 (IL-6). Cardiovascular diseases represent the main cause of morbidity and mortality in persons with excessive weight and obese patients. Atherosclerotic lesions represent a pathological substrate of these illnesses. The aim of our study was to analyze corelations between some specific adipocytokines (such as leptine) and some nonspecific cytokines (such as IL-6, TNFα) with indicators of lipid and carbohydrate metabolism. The study group included 123 persons (100 subjects with overweight and obesity, 23 persons with normal weight).The article present results of studying immune parameters of patients with obesity, including cytokine levels, major classes of immunoglobulins, lymphocyte subpopulations in blood serum, and their interrelations with disturbances of carbohydrate and fat metabolism.
format	article
author	A. F. Salikhova L. M. Farkhutdinova
author_facet	A. F. Salikhova L. M. Farkhutdinova
author_sort	A. F. Salikhova
title	IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES
title_short	IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES
title_full	IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES
title_fullStr	IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES
title_full_unstemmed	IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES
title_sort	immunological features of obesity and their interrelation with violations of a carbohydrate and fatty exchanges
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/1db85244b911426f8fb6bad472456db5
work_keys_str_mv	AT afsalikhova immunologicalfeaturesofobesityandtheirinterrelationwithviolationsofacarbohydrateandfattyexchanges AT lmfarkhutdinova immunologicalfeaturesofobesityandtheirinterrelationwithviolationsofacarbohydrateandfattyexchanges
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IMMUNOLOGICAL FEATURES OF OBESITY AND THEIR INTERRELATION WITH VIOLATIONS OF A CARBOHYDRATE AND FATTY EXCHANGES

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